| Description : |
This gene encodes a member of the G protein-coupled receptor family and regulates brain cortical patterning. The encoded protein binds specifically to transglutaminase 2, a component of tissue and tumor stroma implicated as an inhibitor of tumor progression. Mutations in this gene are associated with a brain malformation known as bilateral frontoparietal polymicrogyria. Alternative splicing results in multiple transcript variants. |
| Source : |
HEK293 |
| Species : |
Human |
| Tag : |
Myc/DDK |
| Molecular Mass : |
77.7 kDa |
| AA Sequence : |
MTPQSLLQTTLFLLSLLFLVQGAHG RGHREDFRFCSQRNQTHRSSLHYKP TPDLRISIENSEEALTVHAPFPAAH PASRSFPDPRGLYHFCLYWNRHAGR LHLLYGKRDFLLSDKASSLLCFQHQ EESLAQGPPLLATSVTSWWSPQNIS LPSAASFTFSFHSPPHTAAHNASVD MCELKRDLQLLSQFLKHPQKASRRP SAAPASQQLQSLESKLTSVRFMGDM VSFEEDRINATVWKLQPTAGLQDLH IHSRQEEEQSEIMEYSVLLPRTLFQ RTKGRSGEAEKRLLLVDFSSQALFQ DKNSSHVLGEKVLGIVVQNTKVANL TEPVVLTFQHQLQPKNVTLQCVFWV EDPTLSSPGHWSSAGCETVRRETQT SCFCNHLTYFAVLMVSSVEVDAVHK HYLSLLSYVGCVVSALACLVTIAAY LCSRVPLPCRRKPRDYTIKVHMNLL LAVFLLDTSFLLSEPVALTGSEAGC RASAIFLHFSLLTCLSWMGLEGYNL YRLVVEVFGTYVPGYLLKLSAMGWG FPIFLVTLVALVDVDNYGPIILAVH RTPEGVIYPSMCWIRDSLVSYITNL GLFSLVFLFNMAMLATMVVQILRLR PHTQKWSHVLTLLGLSLVLGLPWAL IFFSFASGTFQLVVLYLFSIITSFQ GFLIFIWYWSMRLQARGGPSPLKSN SDSARLPISSGSTSSSRITRTRPLE QKLISEEDLAANDILDYKDDDDKV |
| Purity : |
> 80% as determined by SDS-PAGE and Coomassie blue staining |
| Stability : |
Stable for 3 months from receipt of products under proper storage and handling conditions. |
| Storage : |
Store at -80 centigrade. Avoid repeated freeze-thaw cycles. |
| Concentration : |
50 μg/mL as determined by BCA |
| Storage Buffer : |
100 mM glycine, 25 mM Tris-HCl, pH 7.3. |
