Recombinant Human ADH1B Protein, Myc/DDK-tagged, C13 and N15-labeled

• Cat.No.: ADH1B-6574H
• Product Overview: ADH1B MS Standard C13 and N15-labeled recombinant protein (NP_000659) with a C-terminal MYC/DDK tag, was expressed in HEK293 cells.

Specification

• Description: The protein encoded by this gene is a member of the alcohol dehydrogenase family. Members of this enzyme family metabolize a wide variety of substrates, including ethanol, retinol, other aliphatic alcohols, hydroxysteroids, and lipid peroxidation products. This encoded protein, consisting of several homo- and heterodimers of alpha, beta, and gamma subunits, exhibits high activity for ethanol oxidation and plays a major role in ethanol catabolism. Three genes encoding alpha, beta and gamma subunits are tandemly organized in a genomic segment as a gene cluster. Two transcript variants encoding different isoforms have been found for this gene.
• Source: HEK293
• Species: Human
• Tag: Myc/DDK
• Molecular Mass: 39.9 kDa
• AA Sequence: MSTAGKVIKCKAAVLWEVKKPFSIE DVEVAPPKAYEVRIKMVAVGICRTD DHVVSGNLVTPLPVILGHEAAGIVE SVGEGVTTVKPGDKVIPLFTPQCGK CRVCKNPESNYCLKNDLGNPRGTLQ DGTRRFTCRGKPIHHFLGTSTFSQY TVVDENAVAKIDAASPLEKVCLIGC GFSTGYGSAVNVAKVTPGSTCAVFG LGGVGLSAVMGCKAAGAARIIAVDI NKDKFAKAKELGATECINPQDYKKP IQEVLKEMTDGGVDFSFEVIGRLDT MMASLLCCHEACGTSVIVGVPPASQ NLSINPMLLLTGRTWKGAVYGGFKS KEGIPKLVADFMAKKFSLDALITHV LPFEKINEGFDLLHSGKSIRTVLTF TRTRPLEQKLISEEDLAANDILDYK DDDDKV
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Stability: Stable for 3 months from receipt of products under proper storage and handling conditions.
• Storage: Store at -80 centigrade. Avoid repeated freeze-thaw cycles.
• Concentration: 50 μg/mL as determined by BCA
• Storage Buffer: 100 mM glycine, 25 mM Tris-HCl, pH 7.3.

Gene Information

• Gene Name: ADH1B alcohol dehydrogenase 1B (class I), beta polypeptide [ Homo sapiens (human) ]
• Official Symbol: ADH1B
• Synonyms: ADH1B; alcohol dehydrogenase 1B (class I), beta polypeptide; ADH2; alcohol dehydrogenase 1B; ADH, beta subunit; aldehyde reductase; alcohol dehydrogenase subunit beta; alcohol dehydrogenase 2 (class I), beta polypeptide
• Gene ID: 125
• mRNA Refseq: NM_000668
• Protein Refseq: NP_000659
• MIM: 103720
• UniProt ID: P00325