Recombinant Human ADH7 Protein (1-386 aa), His-tagged

• Cat.No.: ADH7-308H
• Product Overview: Recombinant Human ADH7 Protein (1-386 aa) is produced by E. coli expression system. This protein is fused with a 6xHis tag at the N-terminal. Research Area: Metabolism. Protein Description: Full Length.

Specification

• Description: Could function in retinol oxidation for the synthesis of retinoic acid, a hormone important for cellular differentiation. Medium-chain (octanol) and aromatic (m-nitrobenzaldehyde) compounds are the best substrates. Ethanol is not a good substrate but at the high ethanol concentrations reached in the digestive tract, it plays a role in the ethanol oxidation and contributes to the first pass ethanol metabolism.
• Source: E. coli
• Species: Human
• Tag: His
• Form: Tris-based buffer, 50% glycerol
• Molecular Mass: 45.5 kDa
• Protein length: 1-386 aa
• AA Sequence: MFAEIQIQDKDRMGTAGKVIKCKAA VLWEQKQPFSIEEIEVAPPKTKEVR IKILATGICRTDDHVIKGTMVSKFP VIVGHEATGIVESIGEGVTTVKPGD KVIPLFLPQCRECNACRNPDGNLCI RSDITGRGVLADGTTRFTCKGKPVH HFMNTSTFTEYTVVDESSVAKIDDA APPEKVCLIGCGFSTGYGAAVKTGK VKPGSTCVVFGLGGVGLSVIMGCKS AGASRIIGIDLNKDKFEKAMAVGAT ECISPKDSTKPISEVLSEMTGNNVG YTFEVIGHLETMIDALASCHMNYGT SVVVGVPPSAKMLTYDPMLLFTGRT WKGCVFGGLKSRDDVPKLVTEFLAK KFDLDQLITHVLPFKKISEGFELLN SGQSIRTVLTF
• Purity: > 90% as determined by SDS-PAGE.
• Notes: Repeated freezing and thawing is not recommended. Store working aliquots at 4 centigrade for up to one week.
• Storage: The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself. Generally, the shelf life of liquid form is 6 months at -20 centigrade/-80 centigrade. The shelf life of lyophilized form is 12 months at -20 centigrade/-80 centigrade.
• Concentration: A hardcopy of COA with concentration instruction is sent along with the products.

Gene Information

• Gene Name: ADH7 alcohol dehydrogenase 7 (class IV), mu or sigma polypeptide [ Homo sapiens ]
• Official Symbol: ADH7
• Synonyms: ADH7; ADH 4; ADH4
• Gene ID: 131
• mRNA Refseq: NM_000673
• Protein Refseq: NP_000664
• MIM: 600086
• UniProt ID: P40394