Recombinant Human ADPRM Protein, Myc/DDK-tagged, C13 and N15-labeled

• Cat.No.: ADPRM-3066H
• Product Overview: C17orf48 MS Standard C13 and N15-labeled recombinant protein (NP_064618) with a C-terminal MYC/DDK tag, was expressed in HEK293 cells.

Specification

• Description: Hydrolyzes ADP-ribose, IDP-ribose, CDP-glycerol, CDP-choline and CDP-ethanolamine, but not other non-reducing ADP-sugars or CDP-glucose. May be involved in immune cell signaling as suggested by the second-messenger role of ADP-ribose, which activates TRPM2 as a mediator of oxidative/nitrosative stress.
• Source: HEK293
• Species: Human
• Tag: Myc/DDK
• Molecular Mass: 39.3 kDa
• AA Sequence: MDDKPNPEALSDSSERLFSFGVIAD VQFADLEDGFNFQGTRRRYYRHSLL HLQGAIEDWNNESSMPCCVLQLGDI IDGYNAQYNASKKSLELVMDMFKRL KVPVHHTWGNHEFYNFSREYLTHSK LNTKFLEDQIVHHPETMPSEDYYAY HFVPFPKFRFILLDAYDLSVLGVDQ SSPKYEQCMKILREHNPNTELNSPQ GLSEPQFVQFNGGFSQEQLNWLNEV LTFSDTNQEKVVIVSHLPIYPDASD NVCLAWNYRDALAVIWSHECVVCFF AGHTHDGGYSEDPFGVYHVNLEGVI ETAPDSQAFGTVHVYPDKMMLKGRG RVPDRIMNYKKERAFHCTRTRPLEQ KLISEEDLAANDILDYKDDDDKV
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Stability: Stable for 3 months from receipt of products under proper storage and handling conditions.
• Storage: Store at -80 centigrade. Avoid repeated freeze-thaw cycles.
• Concentration: 50 μg/mL as determined by BCA
• Storage Buffer: 100 mM glycine, 25 mM Tris-HCl, pH 7.3.

Gene Information

• Gene Name: ADPRM ADP-ribose/CDP-alcohol diphosphatase, manganese dependent [ Homo sapiens (human) ]
• Official Symbol: ADPRM
• Synonyms: ADPRM; ADP-ribose/CDP-alcohol diphosphatase, manganese dependent; MDS006; C17orf48; NBLA03831; manganese-dependent ADP-ribose/CDP-alcohol diphosphatase; ADP-ribose/CDP-alcohol pyrophosphatase; ADPRibase-Mn; CDP-choline phosphohydrolase; EC 3.6.1.13; EC 3.6.1.16; EC 3.6.1.53
• Gene ID: 56985
• mRNA Refseq: NM_020233
• Protein Refseq: NP_064618
• UniProt ID: Q3LIE5