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Recombinant Human AFAP1L2 Protein, GST-tagged

Cat.No. : AFAP1L2-404H
Product Overview : Human AFAP1L2 full-length ORF ( NP_001001936.1, 1 a.a. - 818 a.a.) recombinant protein with GST-tag at N-terminal.
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  • Gene Information
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Description : AFAP1L2 (Actin Filament Associated Protein 1 Like 2) is a Protein Coding gene. Among its related pathways are Cytoskeletal Signaling. GO annotations related to this gene include SH3 domain binding and protein tyrosine kinase activator activity. An important paralog of this gene is AFAP1.
Source : Wheat Germ
Species : Human
Tag : GST
Molecular Mass : 117.7 kDa
AA Sequence : MERYKALEQLLTELDDFLKILDQEN LSSTALVKKSCLAELLRLYTKSSSS DEEYIYMNKVTINKQQNAESQGKAP EEQGLLPNGEPSQHSSAPQKSLPDL PPPKMIPERKQLAIPKTESPEGYYE EAEPYDTSLNEDGEAVSSSYESYDE EDGSKGKSAPYQWPSPEAGIELMRD ARICAFLWRKKWLGQWAKQLCVIKD NRLLCYKSSKDHSPQLDVNLLGSSV IHKEKQVRKKEHKLKITPMNADVIV LGLQSKDQAEQWLRVIQEVSGLPSE GASEGNQYTPDAQRFNCQKPDIAEK YLSASEYGSSVDGHPEVPETKDVKK KCSAGLKLSNLMNLGRKKSTSLEPV ERSLETSSYLNVLVNSQWKSRWCSV RDNHLHFYQDRNRSKVAQQPLSLVG CEVVPDPSPDHLYSFRILHKGEELA KLEAKSSEEMGHWLGLLLSESGSKT DPEEFTYDYVDADRVSCIVSAAKNS LLLMQRKFSEPNTYIDGLPSQDRQE ELYDDVDLSELTAAVEPTEEATPVA DDPNERESDRVYLDLTPVKSFLHGP SSAQAQASSPTLSCLDNATEALPAD SGPGPTPDEPCIKCPENLGEQQLES LEPEDPSLRITTVKIQTEQQRISFP PSCPDAVVATPPGASPPVKDRLRVT SAEIKLGKNRTEAEVKRYTEEKERL EKKKEEIRGHLAQLRKEKRELKETL LKCTDKEVLASLEQKLKEIDEECRG EESRRVDLELSIMEVKDNLKKAEAG PVTLGTTVDTTHLENVSPRPKAVTP ASAPDCTPVNSATTLKNRPLSVVVT GKGTVLQKAKEWEKKGAS
Applications : Enzyme-linked Immunoabsorbent Assay
Western Blot (Recombinant protein)
Antibody Production
Protein Array
Notes : Best use within three months from the date of receipt of this protein.
Storage : Store at -80centigrade. Aliquot to avoid repeated freezing and thawing.
Storage Buffer : 50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.
Gene Name : AFAP1L2 actin filament associated protein 1-like 2 [ Homo sapiens ]
Official Symbol : AFAP1L2
Synonyms : AFAP1L2; actin filament associated protein 1-like 2; XB130; KIAA1914
Gene ID : 84632
mRNA Refseq : NM_032550.2
Protein Refseq : NP_115939.1
MIM : 612420
UniProt ID : Q8N4X5

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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Q&As (10)

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How does dysregulation or dysfunction of AFAP1L2 protein affect cellular homeostasis, molecular signaling networks, or disease progression? 03/03/2023

Dysregulation or dysfunction of AFAP1L2 protein can disrupt cellular homeostasis, perturb molecular signaling networks, and contribute to disease progression.

What experimental techniques or assays have been used to study the functional significance of AFAP1L2 protein, such as immunoprecipitation, live-cell imaging, or functional assays? 02/03/2023

Various experimental techniques or assays, such as immunoprecipitation, live-cell imaging, or functional assays, have been used to study the functional significance of AFAP1L2 protein.

Are there any genetic variations or mutations in the gene encoding AFAP1L2 protein that impact its expression or function, and what are the implications for cellular processes or disease susceptibility? 06/27/2021

Genetic variations or mutations in the gene encoding AFAP1L2 protein may impact its expression or function, influencing cellular processes or disease susceptibility.

Are there any known post-translational modifications or regulatory mechanisms that modulate the activity or stability of AFAP1L2 protein? 02/14/2021

Post-translational modifications and regulatory mechanisms modulate the activity or stability of AFAP1L2 protein.

Does AFAP1L2 protein interact with specific molecules or participate in protein complexes, and what are the functional implications of these interactions? 01/17/2019

AFAP1L2 protein interacts with specific molecules or forms protein complexes, which have functional implications in cellular processes.

What is the role of AFAP1L2 protein in cellular processes such as actin cytoskeleton dynamics, cell migration, or cell adhesion, and how can its function be investigated experimentally? 09/15/2018

AFAP1L2 protein plays a role in cellular processes such as actin cytoskeleton dynamics, cell migration, or cell adhesion, and its function can be investigated using techniques like siRNA knockdown or overexpression studies.

What is the subcellular localization of AFAP1L2 protein, and how can it be experimentally determined? 06/12/2018

The subcellular localization of AFAP1L2 protein can be experimentally determined using techniques such as immunofluorescence microscopy or subcellular fractionation.

Can AFAP1L2 protein be targeted or manipulated to modulate cellular processes, and what are the potential implications for therapeutic interventions? 04/15/2018

AFAP1L2 protein holds potential as a target for modulating cellular processes, and further research is needed to explore its therapeutic implications and potential interventions.

How is the expression of AFAP1L2 protein regulated, and what factors or signaling pathways control its expression? 03/18/2018

The expression of AFAP1L2 protein is regulated by specific factors and signaling pathways.

How does AFAP1L2 protein contribute to disease development or pathophysiological conditions, and what are the underlying molecular mechanisms? 04/21/2017

AFAP1L2 protein contributes to disease development or pathophysiological conditions, and the underlying molecular mechanisms are currently being investigated.

Customer Reviews (3)

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Reviews
12/07/2022

    Probing protein-protein interactions in DNA damage response for genome stability.

    11/23/2022

      Deciphering protein-protein interactions in intracellular trafficking for cellular transport.

      12/30/2021

        Elucidating protein-protein interactions in cytoskeletal dynamics for cell motility.

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