| Description : |
This gene encodes a metallocarboxypeptidase involved in protein deglutamylation and a member of the peptidase M14 family of proteins. The encoded protein has been described as a "dual-functional" deglutamylase that can remove glutamate residues from both carboxyl termini and side chains of protein substrates. This deglutamylase activity may be important in antiviral immunity. Mutations in this gene are associated with retinitis pigmentosa. |
| Source : |
HEK293 |
| Species : |
Human |
| Tag : |
Myc/DDK |
| Molecular Mass : |
97.4 kDa |
| AA Sequence : |
MELRCGGLLFSSRFDSGNLAHVEKV ESLSSDGEGVGGGASALTSGIASSP DYEFNVWTRPDCAETEFENGNRSWF YFSVRGGMPGKLIKINIMNMNKQSK LYSQGMAPFVRTLPTRPRWERIRDR PTFEMTETQFVLSFVHRFVEGRGAT TFFAFCYPFSYSDCQELLNQLDQRF PENHPTHSSPLDTIYYHRELLCYSL DGLRVDLLTITSCHGLREDREPRLE QLFPDTSTPRPFRFAGKRIFFLSSR VHPGETPSSFVFNGFLDFILRPDDP RAQTLRRLFVFKLIPMLNPDGVVRG HYRTDSRGVNLNRQYLKPDAVLHPA IYGAKAVLLYHHVHSRLNSQSSSEH QPSSCLPPDAPVSDLEKANNLQNEA QCGHSADRHNAEAWKQTEPAEQKLN SVWIMPQQSAGLEESAPDTIPPKES GVAYYVDLHGHASKRGCFMYGNSFS DESTQVENMLYPKLISLNSAHFDFQ GCNFSEKNMYARDRRDGQSKEGSGR VAIYKASGIIHSYTLECNYNTGRSV NSIPAACHDNGRASPPPPPAFPSRY TVELFEQVGRAMAIAALDMAECNPW PRIVLSEHSSLTNLRAWMLKHVRNS RGLSSTLNVGVNKKRGLRTPPKSHN GLPVSCSENTLSRARSFSTGTSAGG SSSSQQNSPQMKNSPSFPFHGSRPA GLPGLGSSTQKVTHRVLGPVREPRS QDRRRQQQPLNHRPAGSLAPSPAPT SSGPASSHKLGSCLLPDSFNIPGSS CSLLSSGDKPEAVMVIGKGLLGTGA RMPCIKTRLQARPRLGRGSPPTRRG MKGSSGPTSPTPRTRESSELELGSC SATPGLPQARPPRPRSAPAFSPISC SLSDSPSWNCYSRGPLGQPEVCFVP KSPPLTVSPRVTRTRPLEQKLISEE DLAANDILDYKDDDDKV |
| Purity : |
> 80% as determined by SDS-PAGE and Coomassie blue staining |
| Stability : |
Stable for 3 months from receipt of products under proper storage and handling conditions. |
| Storage : |
Store at -80 centigrade. Avoid repeated freeze-thaw cycles. |
| Concentration : |
50 μg/mL as determined by BCA |
| Storage Buffer : |
100 mM glycine, 25 mM Tris-HCl, pH 7.3. |
