Recombinant Human AGK Protein, GST-tagged
Cat.No. : | AGK-5753H |
Product Overview : | Human MULK full-length ORF ( NP_060708.1, 1 a.a. - 422 a.a.) recombinant protein with GST-tag at N-terminal. |
- Specification
- Gene Information
- Related Products
Description : | The protein encoded by this gene is a mitochondrial membrane protein involved in lipid and glycerolipid metabolism. The encoded protein is a lipid kinase that catalyzes the formation of phosphatidic and lysophosphatidic acids. Defects in this gene have been associated with mitochondrial DNA depletion syndrome 10. [provided by RefSeq, Feb 2012] |
Source : | Wheat Germ |
Species : | Human |
Tag : | GST |
Molecular Mass : | 73.5 kDa |
AA Sequence : | MTVFFKTLRNHWKKTTAGLCLLTWG GHWLYGKHCDNLLRRAACQEAQVFG NQLIPPNAQVKKATVFLNPAACKGK ARTLFEKNAAPILHLSGMDVTIVKT DYEGQAKKLLELMENTDVIIVAGGD GTLQEVVTGVLRRTDEATFSKIPIG FIPLGETSSLSHTLFAESGNKVQHI TDATLAIVKGETVPLDVLQIKGEKE QPVFAMTGLRWGSFRDAGVKVSKYW YLGPLKIKAAHFFSTLKEWPQTHQA SISYTGPTERPPNEPEETPVQRPSL YRRILRRLASYWAQPQDALSQEVSP EVWKDVQLSTIELSITTRNNQLDPT SKEDFLNICIEPDTISKGDFITIGS RKVRNPKLHVEGTECLQASQCTLLI PEGAGGSFSIDSEEYEAMPVEVKLL PRKLQFFCDPRKREQMLTSPTQ |
Applications : | Enzyme-linked Immunoabsorbent Assay Western Blot (Recombinant protein) Antibody Production Protein Array |
Notes : | Best use within three months from the date of receipt of this protein. |
Storage : | Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing. |
Storage Buffer : | 50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer. |
Gene Name : | AGK acylglycerol kinase [ Homo sapiens ] |
Official Symbol : | AGK |
Synonyms : | AGK; acylglycerol kinase; MULK, multiple substrate lipid kinase; acylglycerol kinase, mitochondrial; FLJ10842; hAGK; hsMuLK; multi-substrate lipid kinase; multiple substrate lipid kinase; MULK; MTDPS10; |
Gene ID : | 55750 |
mRNA Refseq : | NM_018238 |
Protein Refseq : | NP_060708 |
MIM : | 610345 |
UniProt ID : | Q53H12 |
Products Types
◆ Recombinant Protein | ||
AGK-98R | Recombinant Rhesus Macaque AGK Protein, His (Fc)-Avi-tagged | +Inquiry |
AGK-387M | Recombinant Mouse AGK Protein, His (Fc)-Avi-tagged | +Inquiry |
AGK-411H | Recombinant Human AGK Protein, His/GST-tagged | +Inquiry |
AGK-0098H | Recombinant Human AGK Protein (Thr15-Pro300), N-GST-tagged | +Inquiry |
AGK-10252Z | Recombinant Zebrafish AGK | +Inquiry |
◆ Lysates | ||
AGK-1155HCL | Recombinant Human AGK cell lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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Q&As (20)
Ask a questionResearch explores AGK's potential as a target for treating mitochondrial diseases.
AGK's involvement in mitochondrial function affects energy production processes.
AGK participates in regulating cell signaling pathways through its nucleotide exchange activity.
Yes, AGK's roles might intersect with lipid metabolism pathways.
AGK mutations are associated with mitochondrial diseases impacting energy production.
AGK stands for "A-type guanine nucleotide exchange factor," involved in cellular processes.
AGK has a distinctive protein structure that contributes to its cellular functions.
AGK mutations disrupt mitochondrial function, leading to energy production deficits.
AGK's nucleotide exchange activity modulates the activity of GTPase proteins.
AGK's functions contribute to the dynamic changes in cellular membranes.
Mutations in AGK can lead to mitochondrial disorders and related symptoms.
AGK mutations are associated with certain types of cardiomyopathies.
AGK's functions could impact mitochondrial shape and dynamics.
AGK's functions impact cell signaling, vesicle trafficking, and membrane dynamics.
Yes, ongoing research uncovers AGK's multifaceted roles and potential implications.
Research investigates whether AGK is involved in regulating cellular apoptosis.
AGK's functions might intersect with cellular responses to oxidative stress.
AGK's roles extend to intracellular trafficking processes and vesicle transport.
Yes, AGK plays a role in vesicle trafficking, affecting cellular cargo transport.
Mutations in AGK are linked to diseases involving mitochondrial dysfunction.
Customer Reviews (5)
Write a reviewProtein AGK's reliable results helped us uncover key signaling pathways in our experiments.
The protein product’s ability to induce apoptosis provided valuable insights into cell mechanisms.
The protein product’s compatibility with diverse buffer systems ensured stable performance.
The protein product consistently behaved as expected, reinforcing our experimental conclusions.
The high purity of AGK ensured accurate quantification of protein levels.
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