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Recombinant Human AGK Protein, GST-tagged

Cat.No. : AGK-5753H
Product Overview : Human MULK full-length ORF ( NP_060708.1, 1 a.a. - 422 a.a.) recombinant protein with GST-tag at N-terminal.
  • Specification
  • Gene Information
  • Related Products
Description : The protein encoded by this gene is a mitochondrial membrane protein involved in lipid and glycerolipid metabolism. The encoded protein is a lipid kinase that catalyzes the formation of phosphatidic and lysophosphatidic acids. Defects in this gene have been associated with mitochondrial DNA depletion syndrome 10. [provided by RefSeq, Feb 2012]
Source : Wheat Germ
Species : Human
Tag : GST
Molecular Mass : 73.5 kDa
AA Sequence : MTVFFKTLRNHWKKTTAGLCLLTWG GHWLYGKHCDNLLRRAACQEAQVFG NQLIPPNAQVKKATVFLNPAACKGK ARTLFEKNAAPILHLSGMDVTIVKT DYEGQAKKLLELMENTDVIIVAGGD GTLQEVVTGVLRRTDEATFSKIPIG FIPLGETSSLSHTLFAESGNKVQHI TDATLAIVKGETVPLDVLQIKGEKE QPVFAMTGLRWGSFRDAGVKVSKYW YLGPLKIKAAHFFSTLKEWPQTHQA SISYTGPTERPPNEPEETPVQRPSL YRRILRRLASYWAQPQDALSQEVSP EVWKDVQLSTIELSITTRNNQLDPT SKEDFLNICIEPDTISKGDFITIGS RKVRNPKLHVEGTECLQASQCTLLI PEGAGGSFSIDSEEYEAMPVEVKLL PRKLQFFCDPRKREQMLTSPTQ
Applications : Enzyme-linked Immunoabsorbent Assay
Western Blot (Recombinant protein)
Antibody Production
Protein Array
Notes : Best use within three months from the date of receipt of this protein.
Storage : Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing.
Storage Buffer : 50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.
Gene Name : AGK acylglycerol kinase [ Homo sapiens ]
Official Symbol : AGK
Synonyms : AGK; acylglycerol kinase; MULK, multiple substrate lipid kinase; acylglycerol kinase, mitochondrial; FLJ10842; hAGK; hsMuLK; multi-substrate lipid kinase; multiple substrate lipid kinase; MULK; MTDPS10;
Gene ID : 55750
mRNA Refseq : NM_018238
Protein Refseq : NP_060708
MIM : 610345
UniProt ID : Q53H12

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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Q&As (20)

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Can AGK be a therapeutic target? 06/25/2022

Research explores AGK's potential as a target for treating mitochondrial diseases.

How does AGK contribute to cellular energy production? 06/24/2022

AGK's involvement in mitochondrial function affects energy production processes.

How does AGK influence cell signaling? 04/21/2022

AGK participates in regulating cell signaling pathways through its nucleotide exchange activity.

Is AGK relevant to lipid metabolism? 03/08/2022

Yes, AGK's roles might intersect with lipid metabolism pathways.

What's the connection between AGK and mitochondrial disorders? 02/03/2022

AGK mutations are associated with mitochondrial diseases impacting energy production.

What is the AGK protein? 12/23/2021

AGK stands for "A-type guanine nucleotide exchange factor," involved in cellular processes.

How is AGK's structure characterized? 10/08/2021

AGK has a distinctive protein structure that contributes to its cellular functions.

How do AGK mutations impact mitochondrial function? 12/06/2020

AGK mutations disrupt mitochondrial function, leading to energy production deficits.

How does AGK's nucleotide exchange activity work? 10/03/2020

AGK's nucleotide exchange activity modulates the activity of GTPase proteins.

How does AGK impact membrane dynamics? 08/25/2020

AGK's functions contribute to the dynamic changes in cellular membranes.

What's the significance of AGK mutations? 09/15/2019

Mutations in AGK can lead to mitochondrial disorders and related symptoms.

How does AGK relate to cardiomyopathies? 05/31/2019

AGK mutations are associated with certain types of cardiomyopathies.

Can AGK's activities influence mitochondrial morphology? 03/29/2019

AGK's functions could impact mitochondrial shape and dynamics.

What are the applications of AGK? 01/08/2019

AGK's functions impact cell signaling, vesicle trafficking, and membrane dynamics.

Is AGK's research ongoing? 10/12/2018

Yes, ongoing research uncovers AGK's multifaceted roles and potential implications.

Can AGK's roles extend to cellular apoptosis? 09/24/2018

Research investigates whether AGK is involved in regulating cellular apoptosis.

Does AGK influence cellular oxidative stress responses? 07/09/2018

AGK's functions might intersect with cellular responses to oxidative stress.

Can AGK affect intracellular trafficking? 06/08/2018

AGK's roles extend to intracellular trafficking processes and vesicle transport.

Can AGK regulate vesicle trafficking? 03/20/2018

Yes, AGK plays a role in vesicle trafficking, affecting cellular cargo transport.

Are there disease implications for AGK? 02/24/2018

Mutations in AGK are linked to diseases involving mitochondrial dysfunction.

Customer Reviews (5)

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Reviews
06/22/2022

    Protein AGK's reliable results helped us uncover key signaling pathways in our experiments.

    09/05/2021

       The protein product’s ability to induce apoptosis provided valuable insights into cell mechanisms.

      08/04/2017

         The protein product’s compatibility with diverse buffer systems ensured stable performance.

        04/27/2017

           The protein product consistently behaved as expected, reinforcing our experimental conclusions.

          02/11/2016

            The high purity of AGK ensured accurate quantification of protein levels.

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