Recombinant Human AHRR protein, His & GST-tagged

• Cat.No.: AHRR-1698H
• Product Overview: Recombinant Human AHRR aa. (Met1~Pro182 (Accession # A9YTQ3)) fused with N-terminal His & GST tag was produced in E. coli cells.

Specification

• Description: The protein encoded by this gene participates in the aryl hydrocarbon receptor (AhR) signaling cascade, which mediates dioxin toxicity, and is involved in regulation of cell growth and differentiation. It functions as a feedback modulator by repressing AhR-dependent gene expression. Alternatively spliced transcript variants encoding different isoforms have been described for this gene.
• Source: E. coli
• Species: Human
• Tag: His & GST
• Form: Freeze-dried powder
• Molecular Mass: Predicted Molecular Mass: 50.4kDa
• Protein length: Met1~Pro182 (Accession # A9YTQ3)
• Endotoxin: <1.0EU per 1ug (determined by the LAL method)
• Purity: >90%
• Applications: SDS-PAGE; WB; ELISA; IP.
• Stability: The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37°C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.
• Storage: Avoid repeated freeze/thaw cycles. Store at 2-8°C for one month. Aliquot and store at -80°C for 12 months.
• Storage buffer: Supplied as lyophilized form in 20mM Tris, 150mM NaCl, pH8.0, containing 1mM EDTA, 1mM DTT, 0.01% sarcosyl, 5% trehalose, and preservative.
• Reconstitution: Reconstitute in sterile ddH2O.
• Isoelectric Point: 8.8

Gene Information

• Gene Name: AHRR aryl-hydrocarbon receptor repressor [ Homo sapiens (human) ]
• Official Symbol: AHRR
• Synonyms: AHRR; aryl-hydrocarbon receptor repressor; AHH; AHHR; bHLHe77; aryl hydrocarbon receptor repressor; ahR repressor; aryl hydrocarbon hydroxylase regulator; class E basic helix-loop-helix protein 77; dioxin receptor repressor
• Gene ID: 57491
• mRNA Refseq: NM_001242412.1
• Protein Refseq: NP_001229341.1
• UniProt ID: A9YTQ3