Recombinant Human AKAP10 Protein, GST-tagged

• Cat.No.: AKAP10-396H
• Product Overview: Human AKAP10 full-length ORF ( NP_009133.2, 1 a.a. - 662 a.a.) recombinant protein with GST-tag at N-terminal.

Specification

• Description: This gene encodes a member of the A-kinase anchor protein family. A-kinase anchor proteins bind to the regulatory subunits of protein kinase A (PKA) and confine the holoenzyme to discrete locations within the cell. The encoded protein is localized to mitochondria and interacts with both the type I and type II regulatory subunits of PKA. Polymorphisms in this gene may be associated with increased risk of arrhythmias and sudden cardiac death. [provided by RefSeq, May 2012]
• Source: Wheat Germ
• Species: Human
• Tag: GST
• Molecular Mass: 100.2 kDa
• AA Sequence: MRGAGPSPRQSPRTLRPDPGPAMSF FRRKVKGKEQEKTSDVKSIKASISV HSPQKSTKNHALLEAAGPSHVAINA ISANMDSFSSSRTATLKKQPSHMEA AHFGDLGRSCLDYQTQETKSSLSKT LEQVLHDTIVLPYFIQFMELRRMEH LVKFWLEAESFHSTTWSRIRAHSLN TVKQSSLAEPVSPSKKHETTASFLT DSLDKRLEDSGSAQLFMTHSEGIDL NNRTNSTQNHLLLSQECDSAHSLRL EMARAGTHQVSMETQESSSTLTVAS RNSPASPLKELSGKLMKSIEQDAVN TFTKYISPDAAKPIPITEAMRNDII ARICGEDGQVDPNCFVLAQSIVFSA MEQEHFSEFLRSHHFCKYQIEVLTS GTVYLADILFCESALFYFSEYMEKE DAVNILQFWLAADNFQSQLAAKKGQ YDGQEAQNDAMILYDKYFSLQATHP LGFDDVVRLEIESNICREGGPLPNC FTTPLRQAWTTMEKVFLPGFLSSNL YYKYLNDLIHSVRGDEFLGGNVSLT APGSVGPPDESHPGSSDSSASQSSV KKASIKILKNFDEAIIVDAASLDPE SLYQRTYAGKMTFGRVSDLGQFIRE SEPEPDVRKSKGSMFSQAMKKWVQG NTDEAQEELAWKIAKMIVSDIMQQA QYDQPLEKSTKL
• Applications: Enzyme-linked Immunoabsorbent Assay; Western Blot (Recombinant protein); Antibody Production; Protein Array
• Notes: Best use within three months from the date of receipt of this protein.
• Storage: Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing.
• Storage Buffer: 50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.

Gene Information

• Gene Name: AKAP10 A kinase (PRKA) anchor protein 10 [ Homo sapiens ]
• Official Symbol: AKAP10
• Synonyms: AKAP10; A kinase (PRKA) anchor protein 10; A-kinase anchor protein 10, mitochondrial; D AKAP2; dual specificity A kinase anchoring protein 2; MGC9414; mitochondrial A kinase PPKA anchor protein 10; PRKA10; protein kinase A anchoring protein 10; AKAP-10; D-AKAP-2; protein kinase A-anchoring protein 10; a kinase anchor protein 10, mitochondrial; dual specificity A kinase-anchoring protein 2; dual-specificity A-kinase anchoring protein 2; D-AKAP2
• Gene ID: 11216
• mRNA Refseq: NM_007202
• Protein Refseq: NP_009133
• MIM: 604694
• UniProt ID: O43572