Recombinant Human AKIRIN2 Protein, Myc/DDK-tagged, C13 and N15-labeled

• Cat.No.: AKIRIN2-2312H
• Product Overview: AKIRIN2 MS Standard C13 and N15-labeled recombinant protein (NP_060534) with a C-terminal MYC/DDK tag, was expressed in HEK293 cells.

Specification

• Description: Required for the innate immune response. Downstream effector of the Toll-like receptor (TLR), TNF and IL-1 beta signaling pathways leading to the production of IL-6. Forms a complex with YWHAB that acts to repress transcription of DUSP1.
• Source: HEK293
• Species: Human
• Tag: Myc/DDK
• Molecular Mass: 22.5 kDa
• AA Sequence: MACGATLKRTLDFDPLLSPASPKRR RCAPLSAPTSAAASPLSAAAATAAS FSAAAASPQKYLRMEPSPFGDVSSR LTTEQILYNIKQEYKRMQKRRHLET SFQQTDPCCTSDAQPHAFLLSGPAS PGTSSAASSPLKKEQPLFTLRQVGM ICERLLKEREEKVREEYEEILNTKL AEQYDAFVKFTHDQIMRRYGEQPAS YVSTRTRPLEQKLISEEDLAANDIL DYKDDDDKV
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Stability: Stable for 3 months from receipt of products under proper storage and handling conditions.
• Storage: Store at -80 centigrade. Avoid repeated freeze-thaw cycles.
• Concentration: 50 μg/mL as determined by BCA
• Storage Buffer: 100 mM glycine, 25 mM Tris-HCl, pH 7.3.

Gene Information

• Gene Name: AKIRIN2 akirin 2 [ Homo sapiens (human) ]
• Official Symbol: AKIRIN2
• Synonyms: AKIRIN2; akirin 2; C6orf166, chromosome 6 open reading frame 166; akirin-2; dJ486L4.2; FLJ10342; fourteen-three-three beta interactant 1; FBI1; C6orf166
• Gene ID: 55122
• mRNA Refseq: NM_018064
• Protein Refseq: NP_060534
• MIM: 615165
• UniProt ID: Q53H80