Recombinant Human AKR7A3, His-tagged

• Cat.No.: AKR7A3-26149TH
• Product Overview: Recombinant full length Human AKR7A3 fused to His tag at N-terminus; amino acids 1-331 , 41.6kDa.

Specification

• Description: Aldo-keto reductases, such as AKR7A3, are involved in the detoxification of aldehydes and ketones.
• Conjugation: HIS
• Source: E. coli
• Tissue specificity: Expressed in colon, kidney, liver, pancreas, adenocarcinoma and endometrium.
• Form: Liquid
• Purity: >95% by SDS-PAGE
• Storage buffer: Preservative: NoneConstituents: 10% Glycerol, 20mM Tris HCl, 100mM Sodium chloride, pH 8.0
• Storage: Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
• Sequences of amino acids: MRGSHHHHHH GMASMTGGQQ MGRDLYDDDD KDRWGSELEM SRQLSRARPA TVLGAMEMGR RMDAPTSAAV TRAFLERGHT EIDTAFVYSE GQSETILGGL GLRLGGSDCR VKIDTKAIPL FGNSLKPDSL RFQLETSLKR LQCPRVDLFY LHMPDHSTPV EETLRACHQL HQEGKFVELG LSNYAAWEVA EICTLCKSNG WILPTVYQGM YNAITRQVET ELFPCLRHFG LRFYAFNPLA GGLLTGKYKY EDKDGKQPVG RFFGNTWAEM YRNRYWKEHH FEGIALVEKA LQAAYGASAP SMTSATLRWM YHHSQLQGAH GDAVILGMSS LEQLEQNLAA AEEGPLEPAV VDAFNQAWHL VAHECPNYFR
• Sequence Similarities: Belongs to the aldo/keto reductase 2 family.

Gene Information

• Gene Name: AKR7A3 aldo-keto reductase family 7, member A3 (aflatoxin aldehyde reductase) [ Homo sapiens ]
• Official Symbol: AKR7A3
• Synonyms: AKR7A3; aldo-keto reductase family 7, member A3 (aflatoxin aldehyde reductase); aflatoxin B1 aldehyde reductase member 3
• Gene ID: 22977
• mRNA Refseq: NM_012067
• Protein Refseq: NP_036199
• MIM: 608477
• Uniprot ID: O95154
• Chromosome Location: 1p36.13
• Pathway: Metabolism of xenobiotics by cytochrome P450, organism-specific biosystem; Metabolism of xenobiotics by cytochrome P450, conserved biosystem
• Function: aldo-keto reductase (NADP) activity; electron carrier activity; oxidoreductase activity