Recombinant Human ALDH3A1 Protein, GST-tagged

• Cat.No.: ALDH3A1-445H
• Product Overview: Human ALDH3A1 full-length ORF ( AAH04370, 1 a.a. - 453 a.a.) recombinant protein with GST-tag at N-terminal.

Specification

• Description: Aldehyde dehydrogenases oxidize various aldehydes to the corresponding acids. They are involved in the detoxification of alcohol-derived acetaldehyde and in the metabolism of corticosteroids, biogenic amines, neurotransmitters, and lipid peroxidation. The enzyme encoded by this gene forms a cytoplasmic homodimer that preferentially oxidizes aromatic and medium-chain (6 carbons or more) saturated and unsaturated aldehyde substrates. It is thought to promote resistance to UV and 4-hydroxy-2-nonenal-induced oxidative damage in the cornea. The gene is located within the Smith-Magenis syndrome region on chromosome 17. Multiple alternatively spliced variants, encoding the same protein, have been identified. [provided by RefSeq, Sep 2008]
• Source: Wheat Germ
• Species: Human
• Tag: GST
• Molecular Mass: 75.35 kDa
• AA Sequence: MSKISEAVKRARAAFSSGRTRPLQF RIQQLEALQRLIQEQEQELVGALAA DLHKNEWNAYYEEVVYVLEEIEYMI QKLPEWAADEPVEKTPQTQQDELYI HSEPLGVVLVIGTWNYPFNLTIQPM VGAIAAGNAVVLKPSELSENMASLL ATIIPQYLDKDLYPVINGGVPETTE LLKERFDHILYTGSTGVGKIIMTAA AKHLTPVTLELGGKSPCYVDKNCDL DVACRRIAWGKFMNSGQTCVAPDYI LCDPSIQNQIVEKLKKSLKEFYGED AKKSRDYGRIISARHFQRVMGLIEG QKVAYGGTGDAATRYIAPTILTDGD PQSPVMQEEIFGPVLPIVCVRSLEE AIQFINQREKPLALYMFSSNDKVIK KMIAETSSGGVAANDVIVHITLHSL PFGGVGNSGMGSYHGKKSFETFSHR RSCLVRPLMNDGGLKVRYPPSPAKM TQH
• Applications: Enzyme-linked Immunoabsorbent Assay; Western Blot (Recombinant protein); Antibody Production; Protein Array
• Notes: Best use within three months from the date of receipt of this protein.
• Storage: Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing.
• Storage Buffer: 50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.

Gene Information

• Gene Name: ALDH3A1 aldehyde dehydrogenase 3 family, member A1 [ Homo sapiens ]
• Official Symbol: ALDH3A1
• Synonyms: ALDH3A1; aldehyde dehydrogenase 3 family, member A1; ALDH3; aldehyde dehydrogenase, dimeric NADP-preferring; aldehyde dehydrogenase; dimeric NADP preferring; stomach aldehyde dehydrogenase; aldehyde dehydrogenase type III; aldehyde dehydrogenase isozyme 3; ALDHIII; MGC10406
• Gene ID: 218
• mRNA Refseq: NM_000691
• Protein Refseq: NP_000682
• MIM: 100660
• UniProt ID: P30838