Active Recombinant Human ALDOA Protein, His tagged

Cat.No. : ALDOA-1933H
Product Overview : Recombinant human Aldolase A, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography techniques.
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Species : Human
Source : E.coli
Tag : His
Protein Length : 1-364 aa
Description : Fructose bisphosphate aldolase A, also known as Aldolase A is a glycolytic enzyme that catalyzes the reversible conversion of fructose-1, 6-bisphosphate to glyceraldehyde 3-phosphate and dihydroxyacetone phosphate. It is found in the developing embryo and is produced in even greater amounts in adult muscle. Aldolase A expression is repressed in adult liver, kidney and intestine and similar to aldolase C levels in brain and other nervous tissue. Deficiency has been associated with myopathy and hemolytic anemia.
Form : Liquid in 20mM Tris-HCl buffer (pH 8.0) containing 100mM NaCl, 10% glycerol
Bio-activity : Specific activity is > 10 unit/mg, one unit will convert 1.0 μmol of fructose 1,6-diphosphate to dihydroxyacetone phosphate and glyceraldehydes 3-phosphate per minute at pH 7.5 at 37 centigrade.
Molecular Mass : 41.5 kDa
AASequence : < MGSSHHHHHHSSGLVPRGSH> MPYQYPALTPEQKKELSDIAHRIVAPGKGILAADESTGSIAKRLQSIGTENTEENRRFYRQLLLTADDRVNPCIGGVILFHETLYQKADDGRPFPQVIKSKGGVVGIKVDKGVVPLAGTNGETTTQGLDGLSERCAQYKKDGADFAKWRCVLKIGEHTPSALAIMENANVLARYASICQQNGIVPIVEPEILPDGDHDLKRCQYVTEKVLAAVYKALSDHHIYLEGTLLKPNMVTPGHACTQKFSHEEIAMATVTALRRTVPPAVTGITFLSGGQSEEEASINLNAINKCPLLKPWALTFSYGRALQASALKAWGGKKENLKAAQEEYVKRALANSLACQGKYTPSGQAGAAASESLFVSNHAY
Purity : > 95% by SDS-PAGE
Applications : SDS-PAGE, Enzyme Activity
Notes : For research use only. This product is not intended or approved for human, diagnostics or veterinary use.
Storage : Can be stored at +2 to +8 centigrade for 1 week. For long term storage, aliquot and store at -20 to -80 centigrade. Avoid repeated freezing and thawing cycles.
Concentration : 1 mg/mL (determined by Bradford assay)
Gene Name ALDOA aldolase, fructose-bisphosphate A [ Homo sapiens (human) ]
Official Symbol ALDOA
Synonyms ALDOA; aldolase A, fructose-bisphosphate; fructose-bisphosphate aldolase A; muscle-type aldolase; lung cancer antigen NY-LU-1; fructose-1,6-bisphosphate triosephosphate-lyase; ALDA; GSD12
Gene ID 226
mRNA Refseq NM_184041
Protein Refseq NP_908930
MIM 103850
UniProt ID P04075

Not For Human Consumption!

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