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Recombinant Human ALKBH8 Protein, GST-tagged

Cat.No. : ALKBH8-479H
Product Overview : Human ALKBH8 full-length ORF ( NP_620130.1, 1 a.a. - 238 a.a.) recombinant protein with GST-tag at N-terminal.
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  • Gene Information
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Description : ALKBH8 (AlkB Homolog 8, TRNA Methyltransferase) is a Protein Coding gene. Among its related pathways are tRNA processing and Gene Expression. GO annotations related to this gene include nucleic acid binding and nucleotide binding. An important paralog of this gene is KIAA1456.
Source : Wheat Germ
Species : Human
Tag : GST
Molecular Mass : 53.8 kDa
AA Sequence : MDSNHQSNYKLSKTEKKFLRKQIKA KHTLLRHEGIETVSYATQSLVVANG GLGNGVSRNQLLPVLEKCGLVDALL MPPNKPYSFARYRTTEESKRAYVTL NGKEVVDDLGQKITLYLNFVEKVQW KELRPQALPPGLMVVEEIISSEEEK MLLESVDWTEDTDNQNSQKSLKHRR VKHFGYEFHYENNNVDKDKPLSGGL PDICESFLEKWLRKGYIKHKPDQMT INQYEPGQDCHGF
Applications : Enzyme-linked Immunoabsorbent Assay; Western Blot (Recombinant protein); Antibody Production; Protein Array
Notes : Best use within three months from the date of receipt of this protein.
Storage : Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing.
Storage Buffer : 50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.
Gene Name : ALKBH8 alkB, alkylation repair homolog 8 (E. coli) [ Homo sapiens ]
Official Symbol : ALKBH8
Synonyms : ALKBH8; alkB, alkylation repair homolog 8 (E. coli); alkylated DNA repair protein alkB homolog 8; MGC10235; AlkB homologue 8; probable alpha-ketoglutarate-dependent dioxygenase ABH8; tRNA (carboxymethyluridine(34)-5-O)-methyltransferase ABH8; S-adenosyl-L-methionine-dependent tRNA methyltransferase ABH8; ABH8; FLJ38204;
Gene ID : 91801
mRNA Refseq : NM_138775
Protein Refseq : NP_620130
MIM : 613306
UniProt ID : Q96BT7

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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Q&As (16)

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In which populations are mutations in the ALKBH8 gene associated? 04/23/2023

The mutation of ALKBH8 gene is related to individual heredity, age, gender and so on.

Can ALKBH8 gene mutation be modulated by lifestyle? 03/22/2023

Mutations in the ALKBH8 gene can be regulated and influenced by a healthy lifestyle.

What treatments can ALKBH8 gene mutations be treated by? 02/10/2023

There is currently no specific treatment for the ALKBH8 gene mutation, but treatments can be tailored to the symptoms that occur.

What diseases is the ALKBH8 gene associated with? 03/02/2022

The ALKBH8 gene has been linked to breast cancer, neurological diseases and more.

Does ALKBH8 gene mutation affect body immunity? 12/29/2021

Mutations in the ALKBH8 gene may affect the body's immunity, but the exact extent of the impact needs to be further studied.

Is ALKBH8 involved in the immune system? 08/22/2021

The ALKBH8 gene may affect the immune system, but the specific mechanism needs to be further studied.

In which tissues is ALKBH8 gene expressed? 07/30/2021

ALKBH8 gene is expressed in various tissues, including breast, ovary, kidney, brain and so on.

What is the relationship between ALKBH8 gene and hereditary diseases? 06/10/2021

Mutations in the ALKBH8 gene may cause some genetic diseases.

Are mutations in the ALKBH8 gene likely to have long-term consequences? 06/07/2021

Mutations in the ALKBH8 gene may lead to long-term health consequences that need to be studied further.

What physiological processes are related to the expression of ALKBH8 gene? 05/21/2021

The expression of ALKBH8 gene may be related to cell apoptosis, DNA repair and other physiological processes.

What is the inheritance mode of ALKBH8 gene mutation? 11/19/2020

The mutation of ALKBH8 gene may be inherited, and the specific inheritance mode needs to be further studied.

How is the mutation of ALKBH8 gene diagnosed? 04/13/2020

Mutations in the ALKBH8 gene can be diagnosed by methods such as gene sequencing.

What environmental factors are associated with ALKBH8 gene mutation? 04/06/2020

The mutation of ALKBH8 gene may be related to environmental factors such as chemicals and radiation.

What are the symptoms caused by mutation of ALKBH8 gene? 10/18/2019

Mutation of ALKBH8 gene may cause damage to DNA repair, resulting in cell apoptosis obstruction, cell mutation and other problems.

Does mutation of ALKBH8 gene affect fertility? 07/16/2019

Mutations in the ALKBH8 gene may affect fertility, but the exact extent needs to be further studied.

Is the mutation of ALKBH8 gene a cure? 06/01/2019

There is currently no specific cure for mutations in the ALKBH8 gene.

Customer Reviews (3)

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Reviews
10/31/2022

    Good stability and activity during long-term storage.

    03/03/2019

      It is effective and safe in clinical treatment.

      02/08/2019

        ALKBH8 is not structurally or functionally defective.

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