Recombinant Human AMFR, GST-tagged

• Cat.No.: AMFR-3783H
• Product Overview: Autocrine motility factor receptor, isoform 1 (AMFR)

Specification

• Species: Human
• Source: E.Coli/Yeast
• Tag: GST
• Protein Length: 643
• Description: This locus encodes a glycosylated transmembrane receptor. Its ligand, autocrine motility factor, is a tumor motility-stimulating protein secreted by tumor cells. The encoded receptor is also a member of the E3 ubiquitin ligase family of proteins. It catalyzes ubiquitination and endoplasmic reticulum-associated degradation of specific proteins.
• Form: This item requires custom production and lead time is between 5-9 weeks. We can custom produce according to your specifications.
• Purity: >90%
• Notes: Small volumes of AMFR recombinant protein may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice.
• Storage: Store at -20 degree C. For extended storage, store at -20 or -80 degree C.
• Storage Buffer: PBS pH 7.4, 50% glycerol
• Warning: This product is for research use only. Not for use in diagnostic or therapeutic procedures.

Gene Information

• Gene Name: AMFR autocrine motility factor receptor, E3 ubiquitin protein ligase [ Homo sapiens ]
• Official Symbol: AMFR
• Synonyms: AMFR; autocrine motility factor receptor, E3 ubiquitin protein ligase; autocrine motility factor receptor; gp78; RNF45; RING finger protein 45; GP78
• Gene ID: 267
• mRNA Refseq: NM_001144
• Protein Refseq: NP_001135
• MIM: 603243
• UniProt ID: P26442
• Chromosome Location: 16q21
• Pathway: Protein processing in endoplasmic reticulum, organism-specific biosystem; Protein processing in endoplasmic reticulum, conserved biosystem
• Function: ligase activity; metal ion binding; protein binding; receptor activity; receptor activity; ubiquitin-protein ligase activity; ubiquitin-protein ligase activity; zinc ion binding