| Description : |
This gene belongs to the motin family of angiostatin binding proteins characterized by conserved coiled-coil domains and C-terminal PDZ binding motifs. The encoded protein is expressed predominantly in endothelial cells of capillaries as well as larger vessels of the placenta where it may mediate the inhibitory effect of angiostatin on tube formation and the migration of endothelial cells toward growth factors during the formation of new blood vessels. Alternative splicing results in multiple transcript variants encoding different isoforms. |
| Source : |
HEK293 |
| Species : |
Human |
| Tag : |
Myc/DDK |
| Molecular Mass : |
72.6 kDa |
| AA Sequence : |
MPRAQPSSASYQPVPADPFAIVSRA QQMVEILSDENRNLRQELEGCYEKV ARLQKVETEIQRVSEAYENLVKSSS KREALEKAMRNKLEGEIRRMHDFNR DLRERLETANKQLAEKEYEGSEDTR KTISQLFAKNKESQREKEKLEAELA TARSTNEDQRRHIEIRDQALSNAQA KVVKLEEELKKKQVYVDKVEKMQQA LVQLQAACEKREQLEHRLRTRLERE LESLRIQQRQGNCQPTNVSEYNAAA LMELLREKEERILALEADMTKWEQK YLEENVMRHFALDAAATVAAQRDTT VISHSPNTSYDTALEARIQKEEEEI LMANKRCLDMEGRIKTLHAQIIEKD AMIKVLQQRSRKEPSKTEQLSCMRP AKSLMSISNAGSGLLSHSSTLTGSP IMEEKRDDKSWKGSLGILLGGDYRA EYVPSTPSPVPPSTPLLSAHSKTGS RDCSTQTERGTESNKTAAVAPISVP APVAAAATAAAITATAATITTTMVA AAPVAVAAAAAPAAAAAPSPATAAA TAAAVSPAAAGQIPAAASVASAAAV APSAAAAAAVQVAPAAPAPVPAPAL VPVPAPAAAQASAPAQTQAPTSAPA VAPTPAPTPTPAVAQAEVPPASPAT GPGPHRLSIPSLTCNPDKTDGPVFH SNTLERKTPIQILGQEPDAEMVEYL ITRTRPLEQKLISEEDLAANDILDY KDDDDKV |
| Purity : |
> 80% as determined by SDS-PAGE and Coomassie blue staining |
| Stability : |
Stable for 3 months from receipt of products under proper storage and handling conditions. |
| Storage : |
Store at -80 centigrade. Avoid repeated freeze-thaw cycles. |
| Concentration : |
50 μg/mL as determined by BCA |
| Storage Buffer : |
100 mM glycine, 25 mM Tris-HCl, pH 7.3. |
