Recombinant Human ANGPTL3 Protein, Myc/DDK-tagged, C13 and N15-labeled

• Cat.No.: ANGPTL3-842H
• Product Overview: ANGPTL3 MS Standard C13 and N15-labeled recombinant protein (NP_055310) with a C-terminal MYC/DDK tag, was expressed in HEK293 cells.

Specification

• Description: This gene encodes a member of a family of secreted proteins that function in angiogenesis. The encoded protein, which is expressed predominantly in the liver, is further processed into an N-terminal coiled-coil domain-containing chain and a C-terminal fibrinogen chain. The N-terminal chain is important for lipid metabolism, while the C-terminal chain may be involved in angiogenesis. Mutations in this gene cause familial hypobetalipoproteinemia type 2.
• Source: HEK293
• Species: Human
• Tag: Myc/DDK
• Molecular Mass: 53.6 kDa
• AA Sequence: MFTIKLLLFIVPLVISSRIDQDNSS FDSLSPEPKSRFAMLDDVKILANGL LQLGHGLKDFVHKTKGQINDIFQKL NIFDQSFYDLSLQTSEIKEEEKELR RTTYKLQVKNEEVKNMSLELNSKLE SLLEEKILLQQKVKYLEEQLTNLIQ NQPETPEHPEVTSLKTFVEKQDNSI KDLLQTVEDQYKQLNQQHSQIKEIE NQLRRTSIQEPTEISLSSKPRAPRT TPFLQLNEIRNVKHDGIPAECTTIY NRGEHTSGMYAIRPSNSQVFHVYCD VISGSPWTLIQHRIDGSQNFNETWE NYKYGFGRLDGEFWLGLEKIYSIVK QSNYVLRIELEDWKDNKHYIEYSFY LGNHETNYTLHLVAITGNVPNAIPE NKDLVFSTWDHKAKGHFNCPEGYSG GWWWHDECGENNLNGKYNKPRAKSK PERRRGLSWKSQNGRLYSIKSTKML IHPTDSESFETRTRPLEQKLISEED LAANDILDYKDDDDKV
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Stability: Stable for 3 months from receipt of products under proper storage and handling conditions.
• Storage: Store at -80 centigrade. Avoid repeated freeze-thaw cycles.
• Concentration: 50 μg/mL as determined by BCA
• Storage Buffer: 100 mM glycine, 25 mM Tris-HCl, pH 7.3.

Gene Information

• Gene Name: ANGPTL3 angiopoietin-like 3 [ Homo sapiens (human) ]
• Official Symbol: ANGPTL3
• Synonyms: ANGPTL3; angiopoietin-like 3; ANGPT5; angiopoietin-related protein 3; angiopoietin 5; ANG-5; FHBL2
• Gene ID: 27329
• mRNA Refseq: NM_014495
• Protein Refseq: NP_055310
• MIM: 604774
• UniProt ID: Q9Y5C1