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Recombinant Human ANKRD15 protein, GST-tagged

Cat.No. : ANKRD15-576H
Product Overview : Human ANKRD15 partial ORF ( AAH38116, 701 a.a. - 800 a.a.) recombinant protein with GST-tag at N-terminal.
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  • Gene Information
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Description : The protein encoded by this gene belongs to the Kank family of proteins, which contain multiple ankyrin repeat domains. This family member functions in cytoskeleton formation by regulating actin polymerization. This gene is a candidate tumor suppressor for renal cell carcinoma. Mutations in this gene cause cerebral palsy spastic quadriplegic type 2, a central nervous system development disorder. A t(5;9) translocation results in fusion of the platelet-derived growth factor receptor beta gene (PDGFRB) on chromosome 5 with this gene in a myeloproliferative neoplasm featuring severe thrombocythemia. Alternative splicing of this gene results in multiple transcript variants. A related pseudogene has been identified on chromosome 20. [provided by RefSeq, Dec 2014]
Source : Wheat Germ
Species : Human
Tag : GST
Molecular Mass : 36.63 kDa
AA Sequence : MGSLNSQLISTLSSINSVMKSASTE ELRNPDFQKTSLGKITGNYLGYTCK CGGLQSGSPLSSQTSQPEQEVGTSE GKPISSLDAFPTQEGTLSPVNLTDD
Applications : Enzyme-linked Immunoabsorbent Assay; Western Blot (Recombinant protein); Antibody Production; Protein Array
Notes : Best use within three months from the date of receipt of this protein.
Storage : Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing.
Storage Buffer : 50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.
Gene Name : KANK1 KN motif and ankyrin repeat domains 1 [ Homo sapiens (human) ]
Official Symbol : KANK1
Synonyms : KANK1; KN motif and ankyrin repeat domains 1; KANK; CPSQ2; ANKRD15; KN motif and ankyrin repeat domain-containing protein 1; ankyrin repeat domain-containing protein 15; kidney ankyrin repeat-containing protein
Gene ID : 23189
mRNA Refseq : NM_001256876
Protein Refseq : NP_001243805
MIM : 607704
UniProt ID : Q14678

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For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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