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Recombinant Human AP1G2 protein, GST-tagged

Cat.No. : AP1G2-645H
Product Overview : Human AP1G2 partial ORF ( NP_003908, 686 a.a. - 785 a.a.) recombinant protein with GST-tag at N-terminal.
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  • Gene Information
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Description : Adaptins are important components of clathrin-coated vesicles transporting ligand-receptor complexes from the plasma membrane or from the trans-Golgi network to lysosomes. The adaptin family of proteins is compsed of four classes of molecules named alpha, beta-, beta prime- and gamma- adaptins. Adaptins, together with medium and small subunits, form a heterotetrameric complex called an adaptor, whose role is to promote the formation of clathrin-coated pits and vesicles. The protein encoded by this gene is a gamma-adaptin protein and it belongs to the adaptor complexes large subunits family. This protein along with the complex is thought to function at some trafficking step in the complex pathways between the trans-Golgi network and the cell surface. Several alternatively spliced transcript variants of this gene exist, but their full-length nature is not known. [provided by RefSeq, Aug 2
Source : Wheat Germ
Species : Human
Tag : GST
Molecular Mass : 36.74 kDa
AA Sequence : RPPENPALLLITITATNFSEGDVTH FICQAAVPKSLQLQLQAPSGNTVPA RGGLPITQLFRILNPNKAPLRLKLR LTYDHFHQSVQEIFEVNNLPVESWQ
Applications : Enzyme-linked Immunoabsorbent Assay; Western Blot (Recombinant protein); Antibody Production; Protein Array
Notes : Best use within three months from the date of receipt of this protein.
Storage : Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing.
Storage Buffer : 50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.
Gene Name : AP1G2 adaptor related protein complex 1 gamma 2 subunit [ Homo sapiens (human) ]
Official Symbol : AP1G2
Synonyms : AP1G2 adaptor related protein complex 1 gamma 2 subunit; G2AD; AP-1 complex subunit gamma-like 2; clathrin-associated/assembly/adaptor protein, large, gamma-2; gamma2-adaptin
Gene ID : 8906
mRNA Refseq : NM_001282474
Protein Refseq : NP_001269403
MIM : 603534
UniProt ID : O75843

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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Q&As (15)

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Can AP1G2 be directly absorbed through the skin? 09/26/2022

AP1G2 cannot be directly absorbed through the skin because of its large molecular weight and it is not easy to penetrate the skin.

Does AP1G2 cause immune response? 08/01/2022

Recombinant AP1G2 does not cause an immune response under normal use, but may cause an immune response under individual differences or abnormal use.

Can AP1G2 effectively improve brain hypoxia? 05/19/2022

At present, it has not been found that the AP1G2 can effectively improve the brain hypoxia.

Is AP1G2 toxic? 04/24/2022

The recombinant AP1G2 protein is not toxic under normal use, but may cause adverse reactions if the prescribed dosage is exceeded or abnormal reactions occur.

What are the prospects of AP1G2 in the medical field? 01/14/2022

AP1G2 has a wide range of prospects in the medical field, and can be used in the production of biological drugs, disease diagnosis, treatment and prevention.

Does AP1G2 have the function of stimulating the immune system? 08/19/2021

The AP1G2 does not stimulate the immune system because its action is mainly inside the cell.

Is AP1G2 used by intramuscular injection? 06/25/2021

AP1G2 can be used by intramuscular injection, but should be performed by a medical professional and strictly controlled the amount and dosage of the drug.

What is the dose and use method of AP1G2 ? 05/30/2021

The dosage and use method of AP1G2 should follow the corresponding clinical trial regulations and drug standards, and the specific guidance should be provided by a professional doctor.

Can AP1G2 be used in cancer therapy? 09/16/2020

At present, no effective method of recombinant AP1G2 has been found in cancer treatment.

Which diseases can be treated with AP1G2 ? 05/22/2020

There are currently no known recombinant AP1G2 treatment options for a specific disease.

What are the applications of AP1G2 ? 04/25/2020

The AP1G2 can be used in clinical therapy, basic research, drug development and biologics production.

How is the research progress of AP1G2 ? 08/06/2019

At present, AP1G2 has been widely used in biological product production, drug development and other fields, and relevant research progress is also gradually advancing.

What is the pharmacological mechanism of AP1G2 ? 05/24/2019

Recombinant AP1G2 exerts pharmacological effects mainly by influencing membrane transport and local metabolism within cells.

What is the function of AP1G2 ? 04/07/2019

The AP1G2 mainly acts on the transport between the cell membrane and the endoplasmic reticulum, and can affect the local metabolism and internal signaling of cells.

Does AP1G2 have other pharmacological effects? 01/13/2019

AP1G2 has not been found to have any pharmacological effects other than cellular transport and local metabolism.

Customer Reviews (3)

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Reviews
03/21/2021

    AP1G2 activity is maintained for a very long time, can remain active for a long time, and is very stable and reliable.

    03/14/2021

      The catalytic activity is amazing, it can efficiently promote chemical reactions in a short time, and its catalytic effect is unmatched.

      05/14/2020

        The reproducibility of AP1G2 is very good, showing good production process and quality control.

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