Recombinant Human AP1G2 protein, GST-tagged
Cat.No. : | AP1G2-645H |
Product Overview : | Human AP1G2 partial ORF ( NP_003908, 686 a.a. - 785 a.a.) recombinant protein with GST-tag at N-terminal. |
- Specification
- Gene Information
- Related Products
Description : | Adaptins are important components of clathrin-coated vesicles transporting ligand-receptor complexes from the plasma membrane or from the trans-Golgi network to lysosomes. The adaptin family of proteins is compsed of four classes of molecules named alpha, beta-, beta prime- and gamma- adaptins. Adaptins, together with medium and small subunits, form a heterotetrameric complex called an adaptor, whose role is to promote the formation of clathrin-coated pits and vesicles. The protein encoded by this gene is a gamma-adaptin protein and it belongs to the adaptor complexes large subunits family. This protein along with the complex is thought to function at some trafficking step in the complex pathways between the trans-Golgi network and the cell surface. Several alternatively spliced transcript variants of this gene exist, but their full-length nature is not known. [provided by RefSeq, Aug 2 |
Source : | Wheat Germ |
Species : | Human |
Tag : | GST |
Molecular Mass : | 36.74 kDa |
AA Sequence : | RPPENPALLLITITATNFSEGDVTH FICQAAVPKSLQLQLQAPSGNTVPA RGGLPITQLFRILNPNKAPLRLKLR LTYDHFHQSVQEIFEVNNLPVESWQ |
Applications : | Enzyme-linked Immunoabsorbent Assay; Western Blot (Recombinant protein); Antibody Production; Protein Array |
Notes : | Best use within three months from the date of receipt of this protein. |
Storage : | Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing. |
Storage Buffer : | 50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer. |
Gene Name : | AP1G2 adaptor related protein complex 1 gamma 2 subunit [ Homo sapiens (human) ] |
Official Symbol : | AP1G2 |
Synonyms : | AP1G2 adaptor related protein complex 1 gamma 2 subunit; G2AD; AP-1 complex subunit gamma-like 2; clathrin-associated/assembly/adaptor protein, large, gamma-2; gamma2-adaptin |
Gene ID : | 8906 |
mRNA Refseq : | NM_001282474 |
Protein Refseq : | NP_001269403 |
MIM : | 603534 |
UniProt ID : | O75843 |
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Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
Inquiry
- Q&As
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Q&As (15)
Ask a questionAP1G2 cannot be directly absorbed through the skin because of its large molecular weight and it is not easy to penetrate the skin.
Recombinant AP1G2 does not cause an immune response under normal use, but may cause an immune response under individual differences or abnormal use.
At present, it has not been found that the AP1G2 can effectively improve the brain hypoxia.
The recombinant AP1G2 protein is not toxic under normal use, but may cause adverse reactions if the prescribed dosage is exceeded or abnormal reactions occur.
AP1G2 has a wide range of prospects in the medical field, and can be used in the production of biological drugs, disease diagnosis, treatment and prevention.
The AP1G2 does not stimulate the immune system because its action is mainly inside the cell.
AP1G2 can be used by intramuscular injection, but should be performed by a medical professional and strictly controlled the amount and dosage of the drug.
The dosage and use method of AP1G2 should follow the corresponding clinical trial regulations and drug standards, and the specific guidance should be provided by a professional doctor.
At present, no effective method of recombinant AP1G2 has been found in cancer treatment.
There are currently no known recombinant AP1G2 treatment options for a specific disease.
The AP1G2 can be used in clinical therapy, basic research, drug development and biologics production.
At present, AP1G2 has been widely used in biological product production, drug development and other fields, and relevant research progress is also gradually advancing.
Recombinant AP1G2 exerts pharmacological effects mainly by influencing membrane transport and local metabolism within cells.
The AP1G2 mainly acts on the transport between the cell membrane and the endoplasmic reticulum, and can affect the local metabolism and internal signaling of cells.
AP1G2 has not been found to have any pharmacological effects other than cellular transport and local metabolism.
Customer Reviews (3)
Write a reviewAP1G2 activity is maintained for a very long time, can remain active for a long time, and is very stable and reliable.
The catalytic activity is amazing, it can efficiently promote chemical reactions in a short time, and its catalytic effect is unmatched.
The reproducibility of AP1G2 is very good, showing good production process and quality control.
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