| Description : |
The protein encoded by this gene is a subunit of the AP3 adaptor-like complex, which is not clathrin-associated, but is associated with the golgi region, as well as more peripheral structures. The AP-3 complex facilitates the budding of vesicles from the golgi membrane, and may be directly involved in trafficking to lysosomes. This subunit is implicated in intracellular biogenesis and trafficking of pigment granules, and possibly platelet dense granules and neurotransmitter vesicles. Defects in this gene are a cause of a new type of Hermansky-Pudlak syndrome. [provided by RefSeq, Feb 2017] |
| Source : |
Wheat Germ |
| Species : |
Human |
| Tag : |
GST |
| Molecular Mass : |
81.7 kDa |
| AA Sequence : |
MALKMVKGSIDRMFDKNLQDLVRGI RNHKEDEAKYISQCIDEIKQELKQD NIAVKANAVCKLTYLQMLGYDISWA AFNIIEVMSASKFTFKRIGYLAASQ SFHEGTDVIMLTTNQIRKDLSSPSQ YDTGVALTGLSCFVTPDLARDLAND IMTLMSHTKPYIRKKAVLIMYKVFL KYPESLRPAFPRLKEKLEDPDPGVQ SAAVNVICELARRNPKNYLSLAPLF FKLMTSSTNNWVLIKIIKLFGALTP LGPRLGKKLIEPLTNLIHSTSAMSL LYECVNTVIAVLISLSSGMPNHSAS IQLCVQKLRILIEDSDQNLKYLGLL AMSKILKTHPKSVQSHKDLILQCLD DKDESIRLRALDLLYGMVSKKNLME IVKKLMTHVDKAEGTTYRDELLTKI IDICSQSNYQYITNFEWYISILVEL TRLEGTRHGHLIAAQMLDVAIRVKA IRKFAVSQMSALLDSAHLLASSTQR NGICEVLYAAAWICGEFSEHLQEPH HTLEAMLRPRVTTLPGHIQAVYVQN VVKLYASILQQKEQAGEAEGAQAVT QLMVDRLPQFVQSADLEVQERASCI LQLVKHIQKLQAKDVPVAEEVSALF AGELNPVAPKAQKKVPVPEGLDLDA WINEPLSDSESEDERPRAVFHEEEQ RRPKHRPSEADEEELARRREARKQE QANNPFYIKSSPSPQKRYQDTPGVE HIPVVQIDLSVPLKVPGLPMSDQYV KLEEERRHRQKLEKDKR |
| Applications : |
Enzyme-linked Immunoabsorbent Assay; Western Blot (Recombinant protein); Antibody Production; Protein Array |
| Notes : |
Best use within three months from the date of receipt of this protein. |
| Storage : |
Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing. |
| Storage Buffer : |
50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer. |
