Recombinant Human APCS Protein, MYC/DDK-tagged, C13 and N15-labeled

• Cat.No.: APCS-341H
• Product Overview: APCS MS Standard C13 and N15-labeled recombinant protein (NP_001630) with a C-terminal MYC/DDK tag, was expressed in HEK293 cells.

Specification

• Description: The protein encoded by this gene is a glycoprotein, belonging to the pentraxin family of proteins, which has a characteristic pentameric organization. These family members have considerable sequence homology which is thought to be the result of gene duplication. The binding of the encoded protein to proteins in the pathological amyloid cross-beta fold suggests its possible role as a chaperone. This protein is also thought to control the degradation of chromatin. It has been demonstrated that this protein binds to apoptotic cells at an early stage, which raises the possibility that it is involved in dealing with apoptotic cells in vivo. [provided by RefSeq, Sep 2008]
• Source: HEK293
• Species: Human
• Tag: Myc/DDK
• Molecular Mass: 25.4 kDa
• AA Sequence: MNKPLLWISVLTSLLEAFAHTDLSG KVFVFPRESVTDHVNLITPLEKPLQ NFTLCFRAYSDLSRAYSLFSYNTQG RDNELLVYKERVGEYSLYIGRHKVT SKVIEKFPAPVHICVSWESSSGIAE FWINGTPLVKKGLRQGYFVEAQPKI VLGQEQDSYGGKFDRSQSFVGEIGD LYMWDSVLPPENILSAYQGTPLPAN ILDWQALNYEIRGYVIIKPLVWVTR TRPLEQKLISEEDLAANDILDYKDD DDKV
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Stability: Stable for 3 months from receipt of products under proper storage and handling conditions.
• Storage: Store at -80 centigrade. Avoid repeated freeze-thaw cycles.
• Concentration: 50 μg/mL as determined by BCA
• Storage Buffer: 100 mM glycine, 25 mM Tris-HCl, pH 7.3.

Gene Information

• Gene Name: APCS amyloid P component, serum [ Homo sapiens (human) ]
• Official Symbol: APCS
• Synonyms: APCS; amyloid P component, serum; serum amyloid P-component; 9.5S alpha 1 glycoprotein; MGC88159; pentaxin related; PTX2; SAP; pentaxin-related; 9.5S alpha-1-glycoprotein
• Gene ID: 325
• mRNA Refseq: NM_001639
• Protein Refseq: NP_001630
• MIM: 104770
• UniProt ID: P02743