Recombinant Human APOL1, His-tagged

• Cat.No.: APOL1-3575H
• Product Overview: Apolipoprotein L1 (APOL1)

Specification

• Species: Human
• Source: E.Coli/Yeast
• Tag: His
• Protein Length: 398
• Description: This gene encodes a secreted high density lipoprotein which binds to apolipoprotein A-I. Apolipoprotein A-I is a relatively abundant plasma protein and is the major apoprotein of HDL. It is involved in the formation of most cholesteryl esters in plasma and also promotes efflux of cholesterol from cells. This apolipoprotein L family member may play a role in lipid exchange and transport throughout the body, as well as in reverse cholesterol transport from peripheral cells to the liver. Several different transcript variants encoding different isoforms have been found for this gene.
• Form: This item requires custom production and lead time is between 5-9 weeks. We can custom produce according to your specifications.
• Purity: >90%
• Notes: Small volumes of APOL1 recombinant protein may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice.
• Storage: Store at -20 degree C. For extended storage, store at -20 or -80 degree C.
• Storage Buffer: PBS pH 7.4, 50% glycerol
• Warning: This product is for research use only. Not for use in diagnostic or therapeutic procedures.

Gene Information

• Gene Name: APOL1 apolipoprotein L, 1 [ Homo sapiens ]
• Official Symbol: APOL1
• Synonyms: APOL1; apolipoprotein L, 1; APOL; apolipoprotein L1; APO-L; FSGS4; APOL-I
• Gene ID: 8542
• mRNA Refseq: NM_001136540
• Protein Refseq: NP_001130012
• MIM: 603743
• UniProt ID: O14791
• Chromosome Location: 22q13.1
• Pathway: African trypanosomiasis, organism-specific biosystem; African trypanosomiasis, conserved biosystem
• Function: chloride channel activity; lipid binding; protein binding