Recombinant Human APRT protein, His-tagged

• Cat.No.: APRT-20H
• Product Overview: Recombinant Human APRT, fused with N-His, was expressed in E. coli.

Specification

• Species: Human
• Source: E.coli
• Tag: His
• Protein Length: 195aa(including fusion tag)
• Description: Adenine phosphoribosyltransferase belongs to purine/pyrimidine phosphoribosyltransferase family. This enzyme catalyzes the formation of AMP and inorganic pyrophosphate from adenine and 5-phosphoribosyl-1-pyrophosphate (PRPP). It also produces adenine as a by-product of the polyamine biosynthesis pathway. A homozygous deficiency in this enzyme causes 2, 8-dihydroxyadenine urolithiasis. Two transcript variants encoding different isoforms have been found for this gene.
• Form: 20mM Tris.Cl, 50mM NaCl, 50% Glycerol, pH8.0.
• Molecular Mass: 21.5kDa(including fusion tag)
• Applications: WB, ELISA, IP, antibody production, protein array
• Storage: Store at -80°C and avoid repeated freeze-thaw cycles.

Gene Information

• Gene Name: APRT adenine phosphoribosyltransferase [ Homo sapiens ]
• Official Symbol: APRT
• Synonyms: APRT; AMP; MGC125856; MGC125857; MGC129961
• Gene ID: 353
• mRNA Refseq: NM_000485
• Protein Refseq: NP_000476
• UniProt ID: P07741
• Chromosome Location: Metabolic pathways, organism-specific biosystem; Metabolism, organism-specific biosystem; Metabolism of nucleotides, organism-specific biosystem; Purine metabolism, organism-specific biosystem; Purine metabolism, organism-specific biosystem; Purine metabolism, conserved biosystem; Purine salvage, organism-specific biosystem
• Pathway: AMP binding; adenine binding; adenine phosphoribosyltransferase activity; transferase activity, transferring glycosyl groups