Recombinant Human AQP7 protein, GST-tagged

• Cat.No.: AQP7-735H
• Product Overview: Human AQP7 full-length ORF ( NP_001161.1, 1 a.a. - 342 a.a.) recombinant protein with GST-tag at N-terminal.

Specification

• Description: This gene encodes a member of the aquaporin family of water-selective membrane channels. The encoded protein localizes to the plasma membrane and allows movement of water, glycerol and urea across cell membranes. This gene is highly expressed in the adipose tissue where the encoded protein facilitates efflux of glycerol. In the proximal straight tubules of kidney, the encoded protein is localized to the apical membrane and prevents excretion of glycerol into urine. The encoded protein is present in spermatids, as well as in the testicular and epididymal spermatozoa suggesting an important role in late spermatogenesis. Alternative splicing of this gene results in multiple transcript variants encoding different isoforms. This gene is located adjacent to a related aquaporin gene on chromosome 9. Multiple pseudogenes of this gene have been identified. [provided by RefSeq, Dec 2015]
• Source: Wheat Germ
• Species: Human
• Tag: GST
• Molecular Mass: 63.6 kDa
• AA Sequence: MVQASGHRRSTRGSKMVSWSVIAKI QEILQRKMVREFLAEFMSTYVMMVF GLGSVAHMVLNKKYGSYLGVNLGFG FGVTMGVHVAGRISGAHMNAAVTFA NCALGRVPWRKFPVYVLGQFLGSFL AAATIYSLFYTAILHFSGGQLMVTG PVATAGIFATYLPDHMTLWRGFLNE AWLTGMLQLCLFAITDQENNPALPG TEALVIGILVVIIGVSLGMNTGYAI NPSRDLPPRIFTFIAGWGKQVFSNG ENWWWVPVVAPLLGAYLGGIIYLVF IGSTIPREPLKLEDSVAYEDHGITV LPKMGSHEPTISPLTPVSVSPANRS SVHPAPPLHESMALEHF
• Applications: Enzyme-linked Immunoabsorbent Assay; Western Blot (Recombinant protein); Antibody Production; Protein Array
• Notes: Best use within three months from the date of receipt of this protein.
• Storage: Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing.
• Storage Buffer: 50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.

Gene Information

• Gene Name: AQP7 aquaporin 7 [ Homo sapiens ]
• Official Symbol: AQP7
• Synonyms: AQP7; aquaporin 7; AQP7L; aquaporin-7; AQP9; AQPap; AQP-7; aquaporin adipose; aquaglyceroporin-7; GLYCQTL; MGC149555; MGC149556
• Gene ID: 364
• mRNA Refseq: NM_001170
• Protein Refseq: NP_001161
• MIM: 602974
• UniProt ID: O14520