| Description : |
Rap1 is a small GTPase that, through effectors, regulates Rho GTPase signaling. These effectors- Rasip1, Radil, and the protein encoded by this gene- translocate to the cell membrane, where they form a multiprotein complex. This complex is necessary for Rap1-induced inhibition of Rho signaling. Defects in this gene may be a cause of nonsyndromic cleft lip with or without cleft palate. [provided by RefSeq, Jun 2016] |
| Source : |
HEK293 |
| Species : |
Human |
| Tag : |
Myc/DDK |
| Molecular Mass : |
142.1 kDa |
| AA Sequence : |
MIAHKQKKTKKKRAWASGQLSTDIT TSEMGLKSLSSNSIFDPDYIKELVN DIRKFSHMLLYLKEAIFSDCFKEVI HIRLEELLRVLKSIMNKHQNLNSVD LQNAAEMLTAKVKAVNFTEVNEENK NDLFQEVFSSIETLAFTFGNILTNF LMGDVGNDSLLRLPVSRETKSFENV SVESVDSSSEKGNFSPLELDNVLLK NTDSIELALSYAKTWSKYTKNIVSW VEKKLNLELESTRNMVKLAEATRTN IGIQEFMPLQSLFTNALLNDIESSH LLQQTIAALQANKFVQPLLGRKNEM EKQRKEIKELWKQEQNKMLEAENAL KKAKLLCMQRQDEYEKAKSSMFRAE EEHLSSSGGLAKNLNKQLEKKRRLE EEALQKVEEANELYKVCVTNVEERR NDLENTKREILAQLRTLVFQCDLTL KAVTVNLFHMQHLQAASLADSLQSL CDSAKLYDPGQEYSEFVKATNSTEE EKVDGNVNKHLNSSQPSGFGPANSL EDVVRLPDSSNKIEEDRCSNSADIT GPSFIRSWTFGMFSDSESTGGSSES RSLDSESISPGDFHRKLPRTPSSGT MSSADDLDEREPPSPSETGPNSLGT FKKTLMSKAALTHKFRKLRSPTKCR DCEGIVVFQGVECEECLLVCHRKCL ENLVIICGHQKLPGKIHLFGAEFTQ VAKKEPDGIPFILKICASEIENRAL CLQGIYRVCGNKIKTEKLCQALENG MHLVDISEFSSHDICDVLKLYLRQL PEPFILFRLYKEFIDLAKEIQHVNE EQETKKNSLEDKKWPNMCIEINRIL LKSKDLLRQLPASNFNSLHFLIVHL KRVVDHAEENKMNSKNLGVIFGPSL IRPRPTTAPITISSLAEYSNQARLV EFLITYSQKIFDGSLQPQDVMCSIG VVDQGCFPKPLLSPEERDIERSMKS LFFSSKEDIHTSESESKIFERATSF EESERKQNALGKCDACLSDKAQLLL DQEAESASQKIEDGKTPKPLSLKSD RSTNNVERHTPRTKIRPVSLPVDRL LLASPPNERNGRNMGNVNLDKFCKN PAFEGVNRKDAATTVCSKFNGFDQQ TLQKIQDKQYEQNSLTAKTTMIMPS ALQEKGVTTSLQISGDHSINATQPS KPYAEPVRSVREASERRSSDSYPLA PVRAPRTLQPQHWTTFYKPHAPIIS IRGNEEKPASPSAAVPPGTDHDPHG LVVKSMPDPDKASACPGQATGQPKE DSEELGLPDVNPMCQRPRLKRMQQF EDLEDEIPQFVTRTRPLEQKLISEE DLAANDILDYKDDDDKV |
| Purity : |
> 80% as determined by SDS-PAGE and Coomassie blue staining |
| Stability : |
Stable for 3 months from receipt of products under proper storage and handling conditions. |
| Storage : |
Store at -80 centigrade. Avoid repeated freeze-thaw cycles. |
| Concentration : |
50 μg/mL as determined by BCA |
| Storage Buffer : |
100 mM glycine, 25 mM Tris-HCl, pH 7.3. |
