| Description : |
Rho GTPases play a fundamental role in numerous cellular processes that are initiated by extracellular stimuli that work through G protein coupled receptors. The encoded protein may form a complex with G proteins and stimulate Rho-dependent signals. A similar protein in rat interacts with glutamate transporter EAAT4 and modulates its glutamate transport activity. Expression of the rat protein induces the reorganization of the actin cytoskeleton and its overexpression induces the formation of membrane ruffling and filopodia. Two alternative transcripts encoding different isoforms have been described. [provided by RefSeq, Jul 2008] |
| Source : |
HEK293 |
| Species : |
Human |
| Tag : |
Myc/DDK |
| Molecular Mass : |
172.1 kDa |
| AA Sequence : |
MSVRLPQSIDRLSSLSSLGDSAPER KSPSHHRQPSDASETTGLVQRCVII QKDQHGFGFTVSGDRIVLVQSVRPG GAAMKAGVKEGDRIIKVNGTMVTNS SHLEVVKLIKSGAYVALTLLGSSPS SMGISGLQQDPSPAGAPRITSVIPS PPPPPPLPPPQRITGPKPLQDPEVQ KHATQILRNMLRQEEKELQRICEVY SRNPASLLEEQIEGARRRVTQLQLK IQQETGGSVDILPLYGDTSQRPSEG RLSLDSQEGDSGLDSGTERFPSLSE SLMNRNSVLSDPGLDSPRTSPVIMA RVAQHHRRQGSDAAVPSTGDQGVDQ SPKPLIIGPEEDYDPGYFNNESDII FQDLEKLKSRPAHLGVFLRYIFSQA DPSPLLFYLCAEVYQQASPKDSRSL GKDIWNIFLEKNAPLRVKIPEMLQA EIDSRLRNSEDARGVLCEAQEAAMP EIQEQIHDYRTKRTLGLGSLYGEND LLDLDGDPLRERQVAEKQLAALGDI LSKYEEDRSAPMDFALNTYMSHAGI RLREARPSNTAEKAQSAPDKDKWLP FFPKTKKSSNSKKEKDALEDKKRNP ILKYIGKPKSSSQSTFHIPLSPVEV KPGNVRNIIQHFENNQQYDAPEPGT QRLSTGSFPEDLLESDSSRSEIRLG RSESLKGREEMKRSRKAENVPRSRS DVDMDAAAEATRLHQSASSSTSSLS TRSLENPTPPFTPKMGRRSIESPSL GFCTDTLLPHLLEDDLGQLSDLEPE PDAQNWQHTVGKDVVAGLTQREIDR QEVINELFVTEASHLRTLRVLDLIF YQRMKKENLMPREELARLFPNLPEL IEIHNSWCEAMKKLREEGPIIKEIS DLMLARFDGPAREELQQVAAQFCSY QSIALELIKTKQRKESRFQLFMQEA ESHPQCRRLQLRDLIISEMQRLTKY PLLLESIIKHTEGGTSEHEKLCRAR DQCREILKYVNEAVKQTENRHRLEG YQKRLDATALERASNPLAAEFKSLD LTTRKMIHEGPLTWRISKDKTLDLH VLLLEDLLVLLQKQDEKLLLKCHSK TAVGSSDSKQTFSPVLKLNAVLIRS VATDKRAFFIICTSKLGPPQIYELV ALTSSDKNTWMELLEEAVRNATRHP GAAPMPVHPPPPGPREPAQQGPTPS RVELDDSDVFHGEPEPEELPGGTGS QQRVQGKHQVLLEDPEQEGSAEEEE LGVLPCPSTSLDGENRGIRTRNPIH LAFPGPLFMEGLADSALEDVENLRH LILWSLLPGHTMETQAAQEPEDDLT PTPSVISVTSHPWDPGSPGQAPPGG EGDNTQLAGLEGERPEQEDMGLCSL EHLPPRTRNSGIWESPELDRNLAED ASSTEAAGGYKVVRKAEVAGSKVVP ALPESGQSEPGPPEVEGGTKATGNC FYVSMPSGPPDSSTDHSEAPMSPPQ PDSLPAGQTEPQPQLQGGNDDPRRP SRSPPSLALRDVGMIFHTIEQLTLK LNRLKDMELAHRELLKSLGGESSGG TTPVGSFHTEAARWTDGSLSPPAKE PLASDSRNSHELGPCPEDGSDAPLE DSTADAAASPGPTRTRPLEQKLISE EDLAANDILDYKDDDDKV |
| Purity : |
> 80% as determined by SDS-PAGE and Coomassie blue staining |
| Stability : |
Stable for 3 months from receipt of products under proper storage and handling conditions. |
| Storage : |
Store at -80 centigrade. Avoid repeated freeze-thaw cycles. |
| Concentration : |
50 μg/mL as determined by BCA |
| Storage Buffer : |
100 mM glycine, 25 mM Tris-HCl, pH 7.3. |
