Recombinant Human ARHGEF6 protein, GST-tagged ARHGEF6-789H

Recombinant Human ARHGEF6 protein, GST-tagged

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Recombinant Human ARHGEF6 protein, GST-tagged

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Cat.No. : ARHGEF6-789H
Product Overview : Human ARHGEF6 full-length ORF ( NP_004831.1, 1 a.a. - 776 a.a.) recombinant protein with GST-tag at N-terminal.
Description : Rho GTPases play a fundamental role in numerous cellular processes that are initiated by extracellular stimuli that work through G protein coupled receptors. The encoded protein belongs to a family of cytoplasmic proteins that activate the Ras-like family of Rho proteins by exchanging bound GDP for GTP. It may form a complex with G proteins and stimulate Rho-dependent signals. This protein is activated by PI3-kinase. Mutations in this gene can cause X-chromosomal non-specific mental retardation. [provided by RefSeq, Jul 2008]
Source : Wheat Germ
Species : Human
Tag : GST
Molecular Mass : 113.9 kDa
AA Sequence : MNPEEQIVTWLISLG VLESPKKTICDPEEF LKSSLKNGVVLCKLI NRLMPGSVEKFCLDP QTEADCINNINDFLK GCATLQVEIFDPDDL YSGVNFSKVLSTLLA VNKATEDQLSERPCG RSSSLSAANTSQTNP QGAVSSTVSGLQRQS KTVEMTENGSHQLIV KARFNFKQTNEDELS VCKGDIIYVTRVEEG GWWEGTLNGRTGWFP SNYVREIKSSERPLS PKAVKGFETAPLTKN YYTVVLQNILDTEKE YAKELQSLLVTYLRP LQSNNNLSTVEVTSL LGNFEEVCTFQQTLC QALEECSKFPENQHK VGGCLLSLMPHFKSM YLAYCANHPSAVNVL TQHSDELEQFMENQG ASSPGILILTTNLSK PFMRLEKYVTLLQEL ERHMEDTHPDHQDIL KAIVAFKTLMGQCQD LRKRKQLELQILSEP IQAWEGEDIKNLGNV IFMSQVMVQYGACEE KEERYLMLFSNVLIM LSASPRMSGFIYQGK IPIAGTVVTRLDEIE GNDCTFEITGNTVER IVVHCNNNQDFQEWL EQLNRLIRGPASCSS LSKTSSSSCSAHSSF SSTGQPRGPLEPPQI IKPWSLSCLRPAPPL RPSAALGYKERMSYI LKESSKSPKTMKKFL HKRKTERKPSEEEYV IRKSTAALEEDAQIL KVIEAYCTSANFQQG HGSSTRKDSIPQVLL PEEEKLIIEETRSNG QTIMEEKSLVDTVYA LKDEVRELKQENKRM KQCLEEELKSRRDLE KLVRRLLKQTDECIR GESSSKTSILP
Applications : Enzyme-linked Immunoabsorbent Assay; Western Blot (Recombinant protein); Antibody Production; Protein Array
Notes : Best use within three months from the date of receipt of this protein.
Storage : Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing.
Storage Buffer : 50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.
Figure :

12.5% SDS-PAGE Stained with Coomassie Blue.

Gene Name : ARHGEF6 Rac/Cdc42 guanine nucleotide exchange factor (GEF) 6 [ Homo sapiens ]
Official Symbol : ARHGEF6
Synonyms : ARHGEF6; Rac/Cdc42 guanine nucleotide exchange factor (GEF) 6; mental retardation, X linked 46 , MRX46; rho guanine nucleotide exchange factor 6; alpha PIX; alphaPIX; Cool 2; Cool2; KIAA0006; PAK interacting exchange factor; alpha; Rac/Cdc42 guanine exchange factor (GEF) 6; PAK-interacting exchange factor alpha; PAK-interacting exchange factor, alpha; rac/Cdc42 guanine nucleotide exchange factor 6; PIXA; COOL2; MRX46; Cool-2; alpha-PIX;
Gene ID : 9459
mRNA Refseq : NM_004840
Protein Refseq : NP_004831
MIM : 300267
UniProt ID : Q15052

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