Recombinant Human ARPC1A Protein, Myc/DDK-tagged, C13 and N15-labeled

• Cat.No.: ARPC1A-5138H
• Product Overview: ARPC1A MS Standard C13 and N15-labeled recombinant protein (NP_006400) with a C-terminal MYC/DDK tag, was expressed in HEK293 cells.

Specification

• Description: This gene encodes one of seven subunits of the human Arp2/3 protein complex. This subunit is a member of the SOP2 family of proteins and is most similar to the protein encoded by gene ARPC1B. The similarity between these two proteins suggests that they both may function as p41 subunit of the human Arp2/3 complex that has been implicated in the control of actin polymerization in cells. It is possible that the p41 subunit is involved in assembling and maintaining the structure of the Arp2/3 complex. Multiple versions of the p41 subunit may adapt the functions of the complex to different cell types or developmental stages. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
• Source: HEK293
• Species: Human
• Tag: Myc/DDK
• Molecular Mass: 41.6 kDa
• AA Sequence: MSLHQFLLEPITCHAWNRDRTQIAL SPNNHEVHIYKKNGSQWVKAHELKE HNGHITGIDWAPKSDRIVTCGADRN AYVWSQKDGVWKPTLVILRINRAAT FVKWSPLENKFAVGSGARLISVCYF ESENDWWVSKHIKKPIRSTVLSLDW HPNNVLLAAGSCDFKCRVFSAYIKE VDEKPASTPWGSKMPFGQLMSEFGG SGTGGWVHGVSFSASGSRLAWVSHD STVSVADASKSVQVSTLKTEFLPLL SVSFVSENSVVAAGHDCCPMLFNYD DRGCLTFVSKLDIPKQSIQRNMSAM ERFRNMDKRATTEDRNTALETLHQN SITQVSIYEVDKQDCRKFCTTGIDG AMTIWDFKTLESSIQGLRIMTRTRP LEQKLISEEDLAANDILDYKDDDDK V
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Stability: Stable for 3 months from receipt of products under proper storage and handling conditions.
• Storage: Store at -80 centigrade. Avoid repeated freeze-thaw cycles.
• Concentration: 50 μg/mL as determined by BCA
• Storage Buffer: 100 mM glycine, 25 mM Tris-HCl, pH 7.3.

Gene Information

• Gene Name: ARPC1A actin related protein 2/3 complex subunit 1A [ Homo sapiens (human) ]
• Official Symbol: ARPC1A
• Synonyms: ARPC1A; actin related protein 2/3 complex, subunit 1A, 41kDa; actin related protein 2/3 complex, subunit 1A (41 kD); actin-related protein 2/3 complex subunit 1A; actin binding protein (Schizosaccharomyces pombe sop2 like); Arc40; SOP2 like protein; SOP2Hs; SOP2L; SOP2-like protein; actin binding protein (Schizosaccharomyces pombe sop2-like)
• Gene ID: 10552
• mRNA Refseq: NM_006409
• Protein Refseq: NP_006400
• MIM: 604220
• UniProt ID: Q92747