Recombinant Human ARR3 protein, GST-tagged

• Cat.No.: ARR3-854H
• Product Overview: Human ARR3 full-length ORF ( AAH12096, 1 a.a. - 359 a.a.) recombinant protein with GST-tag at N-terminal.

Specification

• Description: The protein encoded by this gene is a non-visual arrestin which binds to agonist-activated, phosphorylated G protein-coupled receptors. This binding uncouples the receptor from the heterotrimeric G protein, resulting in termination of the G protein-coupled receptor signaling. The encoded protein also is a part of the centrosome, interacting with gamma-tubulin to help regulate proper centrosome function. [provided by RefSeq, May 2016]
• Source: Wheat Germ
• Species: Human
• Tag: GST
• Molecular Mass: 65.01 kDa
• AA Sequence: MSKVFKKTSSNGKLSIYLGKRDFVD HVDTVEPIDGVVLVDPEYFKCRKLF VMLTCAFRYGRDDLEVIGLTFRKDL YVQTLQVVPAESSSPQGPLTVLQER LLHKLGDNAYPFTLQMVTNLPCSVT LQPGPEDAGKPCGIDFEVKSFCAEN PEETVSKRDYVRLVVRKVQFAPPEA GPGPSAQTIRRFLLSAQPLQLQAWM DREVHYHGEPISVNVSINNCTNKVI KKIKISVDQITDVVLYSLDKYTKTV FIQEFTETVAANSSFSQSFAVTPIL AASCQKRGLALDGKLKHEDTNLASS TIIRPGMDKELLGILVSYKVRVNLM VSCGGILGDLTASDVGVELPLVLIH PKPSYEAAR
• Applications: Enzyme-linked Immunoabsorbent Assay; Western Blot (Recombinant protein); Antibody Production; Protein Array
• Notes: Best use within three months from the date of receipt of this protein.
• Storage: Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing.
• Storage Buffer: 50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.

Gene Information

• Gene Name: ARR3 arrestin 3, retinal (X-arrestin) [ Homo sapiens ]
• Official Symbol: ARR3
• Synonyms: ARR3; arrestin 3, retinal (X-arrestin); arrestin-C; arrestin 4; ARRX; cArr; C-arrestin; X-arrestin; cone arrestin; retinal cone arrestin-3
• Gene ID: 407
• mRNA Refseq: NM_004312
• Protein Refseq: NP_004303
• MIM: 301770
• UniProt ID: P36575