Recombinant Human Arsenic (+3 oxidation state) Methyltransferase, His-tagged

• Cat.No.: AS3MT-6784H
• Product Overview: Recombinant humanAS3MT protein, fused to His-tag at N-terminus, was expressed in E.coli andpurified by using conventional chromatography techniques

Specification

• Cat. No.: AS3MT-6784H
• Description: AS3MT catalyzes thetransfer of a methyl group from S-adenosyl-L-methionine (AdoMet) to trivalentarsenical and may play a role in arsenic metabolism
• Form: Liquid. 20mMTris-HCl buffer (pH8.0) containing 10% glycerol 0.15M NaCl
• Molecular Weight: 44.3kDa(399aa),confirmed by MALDI-TOF
• Purity: > 90% by SDS -PAGE
• Concentration: 1 mg/ml (determinedby Bradford assay)
• Sequences of aminoacids: MGSSHHHHHHSSGLVPRGSH MGSHMAALRD AEIQKDVQTY YGQVLKRSAD LQTNGCVTTA RPVPKHIREA LQNVHEEVALRYYGCGLVIP EHLENCWILD LGSGSGRDCY VLSQLVGEKG HVTGIDMTKG QVEVAEKYLD YHMEKYGFQASNVTFIHGYI EKLGEAGIKN ESHDIVVSNC VINLVPDKQQ VLQEAYRVLK HGGELYFSDV YTSLELPEEIRTHKVLWGEC LGGALYWKEL AVLAQKIGFC PPRLVTANLI TIQNKELERV IGDCRFVSAT FRLFKHSKTGPTKRCQVIYN GGITGHEKEL MFDANFTFKE GEIVEVDEET AAILKNSRFA QDFLIRPIGE KLPTSGGCSALELKDIITDP FKLAEESDSM KSRCVPDAAG GCCGTKKSC
• Storage: Can be stored at+4°C short term (1-2 weeks). For long term storage, aliquot and store at-20°C or -70°C. Avoid repeated freezing and thawing cycles.

Gene Information

• Gene Name: AS3MTarsenic (+3 oxidation state) methyltransferase [ Homo sapiens ]
• Official Symbol: AS3MT
• Synonyms: AS3MT; arsenic (+3 oxidation state)methyltransferase; arsenite methyltransferase; CYT19; 2310045H08Rik; Arsenic(+3 oxidation state) methyltransferase; Arsenite methyltransferase; AS3MT;C10ORF32; CYT19; Cyt19 protein; Hypothetical protein C10orf32; Methylarsonitemethyltransferase; Methyltransferase cyt19; OTTHUMP00000020384;RP11-753C18.6; S adenosylmethionine arsenic (III) methyltransferase;OTTHUMP00000020384; methyltransferase cyt19; methylarsonitemethyltransferase; S-adenosylmethionine:arsenic (III) methyltransferase;S-adenosyl-L-methionine:arsenic(III) methyltransferase; RP11-753C18.6
• Gene ID: 57412
• mRNA Refseq: NM_020682
• Protein Refseq: NP_065733
• MIM: 611806
• Uniprot ID: Q9HBK9
• Chromosome Location: 10q24.33
• Pathway: arsenate detoxification I,conserved biosystem
• Function: arsenite methyltransferaseactivity; methylarsonite methyltransferase activity; methyltransferaseactivity; transferase activity