Recombinant Human ART1 Protein (23-295 aa), His-tagged
Cat.No. : | ART1-1335H |
Product Overview : | Recombinant Human ART1 Protein (23-295 aa) is produced by Yeast expression system. This protein is fused with a 6xHis tag at the N-terminal. Research Area: Epigenetics and Nuclear Signaling. Protein Description: Full Length of Mature Protein. |
- Specification
- Gene Information
- Related Products
Description : | Has ADP-ribosyltransferase activity toward GLP1R. |
Source : | Yeast |
Species : | Human |
Tag : | His |
Form : | Tris-based buffer,50% glycerol |
Molecular Mass : | 32.5 kDa |
Protein length : | 23-295 aa |
AA Sequence : | QSHPITRRDLFSQEIQLDMALASFD DQYAGCAAAMTAALPDLNHTEFQAN QVYADSWTLASSQWQERQARWPEWS LSPTRPSPPPLGFRDEHGVALLAYT ANSPLHKEFNAAVREAGRSRAHYLH HFSFKTLHFLLTEALQLLGSGQRPP RCHQVFRGVHGLRFRPAGPRATVRL GGFASASLKHVAAQQFGEDTFFGIW TCLGAPIKGYSFFPGEEEVLIPPFE TFQVINASRLAQGPARIYLRALGKH STYNCEYIKDKKCKSGPCHLDNS |
Purity : | > 90% as determined by SDS-PAGE. |
Notes : | Repeated freezing and thawing is not recommended. Store working aliquots at 4 centigrade for up to one week. |
Storage : | The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself. Generally, the shelf life of liquid form is 6 months at -20 centigrade/-80 centigrade. The shelf life of lyophilized form is 12 months at -20 centigrade/-80 centigrade. |
Concentration : | A hardcopy of COA with reconstitution instruction is sent along with the products. Please refer to it for detailed information. |
Gene Name : | ART1 ADP-ribosyltransferase 1 [ Homo sapiens ] |
Official Symbol : | ART1 |
Synonyms : | ART1; ART2; CD296; RT6; MGC133217; |
Gene ID : | 417 |
mRNA Refseq : | NM_004314 |
Protein Refseq : | NP_004305 |
MIM : | 601625 |
UniProt ID : | P52961 |
Products Types
◆ Recombinant Protein | ||
ART1-100H | Recombinant Human ART1 Protein, His-tagged | +Inquiry |
ART1-3301H | Recombinant Human ART1 protein(Met1-Asn294), His-tagged | +Inquiry |
ART1-2823H | Recombinant Human ART1 Protein, His-tagged | +Inquiry |
Art1-248M | Recombinant Mouse Art1 Protein, His-tagged | +Inquiry |
ART1-1214C | Recombinant Cynomolgus ART1 Protein, His-tagged | +Inquiry |
◆ Lysates | ||
ART1-8672HCL | Recombinant Human ART1 293 Cell Lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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Q&As (7)
Ask a questionART1 transfers ADP-ribose from nicotinamide adenine dinucleotide (NAD+) to specific arginine residues on substrate proteins, modifying their structure and function.
ART1 predominantly ADP-ribosylates arginine residues on G protein-coupled receptors (GPCRs), such as the P2Y purinergic receptor.
Some pathogens produce enzymes called ADP-ribosyltransferase toxins that can inhibit ART1 activity and evade the immune response.
ART1 is primarily expressed in the testes, but it can also be found in other tissues such as the spleen, kidney, and liver.
Aside from its enzymatic role in ADP-ribosylation, ART1 does not have any known non-enzymatic functions or specific protein interactions.
Mutations in the ART1 gene have not been directly linked to specific diseases or disorders in humans so far.
The activity of ART1 is dependent on the presence of NAD+ as a substrate, and it can be modulated by other factors, including pH and the presence of certain ions.
Customer Reviews (3)
Write a reviewOne aspect that sets the ART1 protein apart is the excellent technical support provided by the manufacturer.
Its purity and reliability have consistently resulted in successful outcomes in my research projects, providing me with accurate and reproducible data.
The ART1 protein has demonstrated remarkable stability, allowing for extended storage without compromising its quality.
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