Recombinant Human ASAP3 Protein, GST-tagged

• Cat.No.: ASAP3-2438H
• Product Overview: Human DDEFL1 full-length ORF ( NP_060177.2, 1 a.a. - 903 a.a.) recombinant protein with GST-tag at N-terminal.

Specification

• Description: This gene encodes a member of a subfamily of ADP-ribosylation factor(Arf) GTPase-activating proteins that contain additional ankyrin repeat and pleckstrin homology domains. The Arf GAP domain of this protein catalyzes the hydrolysis of GTP bound to Arf proteins. The encoded protein promotes cell differentiation and migration and has been implicated in cancer cell invasion. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2009]
• Source: Wheat Germ
• Species: Human
• Tag: GST
• Molecular Mass: 125.6 kDa
• AA Sequence: MPEQFSVAEFLAVTAEDLSSPAGAA AFAAKMPRYRGAALAREEILEGDQA ILQRIKKAVRAIHSSGLGHVENEEQ YREAVESLGNSHLSQNSHELSTGFL NLAVFTREVAALFKNLIQNLNNIVS FPLDSLMKGQLRDGRQDSKKQLEKA WKDYEAKMAKLEKERDRARVTGGIP GEVAQDMQRERRIFQLHMCEYLLKA GESQMKQGPDFLQSLIKFFHAQHNF FQDGWKAAQSLFPFIEKLAASVHAL HQAQEDELQKLTQLRDSLRGTLQLE SREEHLSRKNSGCGYSIHQHQGNKQ FGTEKVGFLYKKSDGIRRVWQKRKC GVKYGCLTISHSTINRPPVKLTLLT CQVRPNPEEKKCFDLVTHNRTYHFQ AEDEHECEAWVSVLQNSKDEALSSA FLGEPSAGPGSWGSAGHDGEPHDLT KLLIAEVKSRPGNSQCCDCGAADPT WLSTNLGVLTCIQCSGVHRELGVRF SRMQSLTLDLLGPSELLLALNMGNT SFNEVMEAQLPSHGGPKPSAESDMG TRRDYIMAKYVEHRFARRCTPEPQR LWTAICNRDLLSVLEAFANGQDFGQ PLPGPDAQAPEELVLHLAVKVANQA SLPLVDFIIQNGGHLDAKAADGNTA LHYAALYNQPDCLKLLLKGRALVGT VNEAGETALDIARKKHHKECEELLE QAQAGTFAFPLHVDYSWVISTEPGS DSEEDEEEKRCLLKLPAQAHWASGR LDISNKTYETVASLGAATPQGESED CPPPLPVKNSSRTLVQGCARHASGD RSEVSSLSSEAPETPESLGSPASSS SLMSPLEPGDPSQAPPNSEEGLREP PGTSRPSLTSGTTPSEMYLPVRFSS ESTRSYRRGARSPEDGPSARQPLPR RNVPVGITEGDGSRTGSLPASSVQL LQD
• Applications: Enzyme-linked Immunoabsorbent Assay
  Western Blot (Recombinant protein)
  Antibody Production
  Protein Array
• Notes: Best use within three months from the date of receipt of this protein.
• Storage: Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing.
• Storage Buffer: 50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.

Gene Information

• Gene Name: ASAP3 ArfGAP with SH3 domain, ankyrin repeat and PH domain 3 [ Homo sapiens ]
• Official Symbol: ASAP3
• Synonyms: ASAP3; ArfGAP with SH3 domain, ankyrin repeat and PH domain 3; DDEFL1, development and differentiation enhancing factor like 1; arf-GAP with SH3 domain, ANK repeat and PH domain-containing protein 3; centaurin; beta 6; CENTB6; FLJ20199; UPLC1; centaurin, beta 6; ARF6 GTPase-activating protein; protein up-regulated in liver cancer 1; up-regulated in liver cancer 1 (UPLC1); development and differentiation enhancing factor-like 1; development and differentiation-enhancing factor-like 1; ArfGAP with SH3 domain, ankyrin repeat and PH domain 3 1; ACAP4; DDEFL1
• Gene ID: 55616
• mRNA Refseq: NM_001143778
• Protein Refseq: NP_001137250
• MIM: 616594
• UniProt ID: Q8TDY4