Recombinant Human ASCL1 Protein, Myc/DDK-tagged, C13 and N15-labeled

• Cat.No.: ASCL1-4032H
• Product Overview: ASCL1 MS Standard C13 and N15-labeled recombinant protein (NP_004307) with a C-terminal MYC/DDK tag, was expressed in HEK293 cells.

Specification

• Description: This gene encodes a member of the basic helix-loop-helix (BHLH) family of transcription factors. The protein activates transcription by binding to the E box (5'-CANNTG-3'). Dimerization with other BHLH proteins is required for efficient DNA binding. This protein plays a role in the neuronal commitment and differentiation and in the generation of olfactory and autonomic neurons. Mutations in this gene may contribute to the congenital central hypoventilation syndrome (CCHS) phenotype in rare cases.
• Source: HEK293
• Species: Human
• Tag: Myc/DDK
• Molecular Mass: 25.5 kDa
• AA Sequence: MESSAKMESGGAGQQPQPQPQQPFL PPAACFFATAAAAAAAAAAAAAQSA QQQQQQQQQQQQAPQLRPAADGQPS GGGHKSAPKQVKRQRSSSPELMRCK RRLNFSGFGYSLPQQQPAAVARRNE RERNRVKLVNLGFATLREHVPNGAA NKKMSKVETLRSAVEYIRALQQLLD EHDAVSAAFQAGVLSPTISPNYSND LNSMAGSPVSSYSSDEGSYDPLSPE EQELLDFTNWFTRTRPLEQKLISEE DLAANDILDYKDDDDKV
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Stability: Stable for 3 months from receipt of products under proper storage and handling conditions.
• Storage: Store at -80 centigrade. Avoid repeated freeze-thaw cycles.
• Concentration: 50 μg/mL as determined by BCA
• Storage Buffer: 100 mM glycine, 25 mM Tris-HCl, pH 7.3.

Gene Information

• Gene Name: ASCL1 achaete-scute family bHLH transcription factor 1 [ Homo sapiens (human) ]
• Official Symbol: ASCL1
• Synonyms: ASCL1; achaete-scute complex homolog 1 (Drosophila); achaete scute complex (Drosophila) homolog like 1, achaete scute complex like 1 (Drosophila); achaete-scute homolog 1; ASH1; bHLHa46; HASH1; ASH-1; achaete scute protein; achaete-scute complex-like 1; class A basic helix-loop-helix protein 46; MASH1
• Gene ID: 429
• mRNA Refseq: NM_004316
• Protein Refseq: NP_004307
• MIM: 100790
• UniProt ID: P50553