Description : |
This gene belongs to the superfamily of acid-sensing ion channels, which are proton-gated, amiloride-sensitive sodium channels. These channels have been implicated in synaptic transmission, pain perception as well as mechanoperception. This gene is predominantly expressed in the pituitary gland, and was considered a candidate for paroxysmal dystonic choreoathetosis (PDC), a movement disorder, however, no correlation was found between mutations in this gene and PDC. |
Source : |
HEK293 |
Species : |
Human |
Tag : |
Myc/DDK |
Molecular Mass : |
72 kDa |
AA Sequence : |
MLSGAAGAARRGGAALAPSLTRSLA GTHAGADSCAGADKGSHKETIEERD KRQQRQQRQRQHQGCGAAGSGSDSP TSGPHPVPVLFPLALSLEEQPLPPL PLGRAPGLLAREGQGREALASPSSR GQMPIEIVCKIKFAEEDAKPKEKEA GDEQSLLGAVAPGAAPRDLATFAST STLHGLGRACGPGPHGLRRTLWALA LLTSLAAFLYQAAGLARGYLTRPHL VAMDPAAPAPVAGFPAVTLCNINRF RHSALSDADIFHLANLTGLPPKDRD GHRAAGLRYPEPDMVDILNRTGHQL ADMLKSCNFSGHHCSASNFSVVYTR YGKCYTFNADPRSSLPSRAGGMGSG LEIMLDIQQEEYLPIWRETNETSFE AGIRVQIHSQEEPPYIHQLGFGVSP GFQTFVSCQEQRLTYLPQPWGNCRA ESELREPELQGYSAYSVSACRLRCE KEAVLQRCHCRMVHMPDSLGGGPEG PCFCPTPCNLTRYGKEISMVRIPNR GSARYLARKYNRNETYIRENFLVLD VFFEALTSEAMEQRAAYGLSALLGD LGGQMGLFIGASILTLLEILDYIYE VSWDRLKRVWRRPKTPLRTSTGGIS TLGLQELKEQSPCPSLGRAEGGGVS SLLPNHHHPHGPPGGLFEDFACTRT RPLEQKLISEEDLAANDILDYKDDD DKV |
Purity : |
> 80% as determined by SDS-PAGE and Coomassie blue staining |
Stability : |
Stable for 3 months from receipt of products under proper storage and handling conditions. |
Storage : |
Store at -80 centigrade. Avoid repeated freeze-thaw cycles. |
Concentration : |
50 μg/mL as determined by BCA |
Storage Buffer : |
100 mM glycine, 25 mM Tris-HCl, pH 7.3. |