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Recombinant Human ASS1 Protein, Myc/DDK-tagged

Cat.No. : ASS1-646H
Product Overview : Recombinant protein of human argininosuccinate synthetase 1 (ASS1), transcript variant 1 with a C-Myc/DDK tag was expressed in HEK293T.
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Description : The protein encoded by this gene catalyzes the penultimate step of the arginine biosynthetic pathway. There are approximately 10 to 14 copies of this gene including the pseudogenes scattered across the human genome, among which the one located on chromosome 9 appears to be the only functional gene for argininosuccinate synthetase. Mutations in the chromosome 9 copy of this gene cause citrullinemia. Two transcript variants encoding the same protein have been found for this gene.
Source : HEK293T
Species : Human
Tag : Myc/DDK
Molecular Mass : 46.3 kDa
Purity : > 80% as determined by SDS-PAGE and Coomassie blue staining
Stability : Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
Storage : Store at -80 centigrade.
Concentration : >50 μg/mL as determined by microplate BCA method
Storage Buffer : 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol
Gene Name : ASS1 argininosuccinate synthase 1 [ Homo sapiens (human) ]
Official Symbol : ASS1
Synonyms : ASS1; argininosuccinate synthase 1; ASS; CTLN1; argininosuccinate synthase; argininosuccinate synthetase 1; citrulline-aspartate ligase; epididymis secretory sperm binding protein; EC 6.3.4.5
Gene ID : 445
mRNA Refseq : NM_000050
Protein Refseq : NP_000041
MIM : 603470
UniProt ID : P00966

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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Q&As (7)

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What are the mechanisms by which ASS1 modulates cell growth and proliferation? 08/06/2022

ASS1 regulates cell growth by controlling the availability of arginine, a key amino acid for cell proliferation.

How does ASS1 deficiency contribute to the development of urea cycle disorders and hyperammonemia? 08/05/2020

ASS1 deficiency leads to urea cycle disorders, causing hyperammonemia and metabolic imbalances.

What is the impact of ASS1 on amino acid metabolism and overall cellular function? 07/01/2020

ASS1 affects amino acid metabolism, playing a critical role in cellular health and function.

How does ASS1 (Argininosuccinate Synthase 1) function in the urea cycle and nitrogen metabolism? 12/21/2019

ASS1 is essential in the urea cycle, converting nitrogen waste into urea for excretion and maintaining nitrogen balance.

How do alterations in ASS1 expression or activity affect cardiovascular health and disease? 09/30/2019

Variations in ASS1 activity can impact cardiovascular health, influencing nitric oxide production and vascular function.

What role does ASS1 play in the synthesis of arginine and its impact on nitric oxide production? 07/27/2018

ASS1 is involved in arginine synthesis, impacting nitric oxide levels and vascular function.

How does ASS1 influence the response to high-protein diets or dietary restrictions in metabolic health? 07/26/2018

ASS1 influences how the body metabolizes high-protein diets, affecting metabolic responses and health.

Customer Reviews (3)

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Reviews
09/04/2020

    Critical expertise in protein engineering, a trusted research resource.

    10/01/2019

      Dependable peptide synthesis, accelerates our peptide-based projects effectively.

      08/10/2018

        Efficient protein purification, cost-effective and dependable.

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