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Recombinant Human ATAD3A protein, GST-tagged

Cat.No. : ATAD3A-930H
Product Overview : Human ATAD3A full-length ORF (BAC03595.1, 1 a.a. - 634 a.a.) recombinant protein with GST-tag at N-terminal.
  • Specification
  • Gene Information
  • Related Products
Description : This gene encodes a ubiquitously expressed mitochondrial membrane protein that contributes to mitochondrial dynamics, nucleoid organization, protein translation, cell growth, and cholesterol metabolism. This gene is a member of the ATPase family AAA-domain containing 3 gene family which, in humans, includes two other paralogs. Naturally occurring mutations in this gene are associated with distinct neurological syndromes including Harel-Yoon syndrome. High-level expression of this gene is associated with poor survival in breast cancer patients. A homozygous knockout of the orthologous gene in mice results in embryonic lethality at day 7.5 due to growth retardation and defective development of the trophoblast lineage. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Feb 2017]
Source : Wheat Germ
Species : Human
Tag : GST
Molecular Mass : 97.8 kDa
AA Sequence : MSWLFGINKGPKGEGAGPPPPLPPA QPGAEGGGDRGLGDRPAPKDKWSNF DPTGLERAAKAARELEHSRYAKDAL NLAQMQEQTLQLEQQSKLKMRLEAL SLLHTLVWAWSLCRAGAVQTQERLS GSASPEQVPAGECCALQEYEAAVEQ LKSEQIRAQAEERRKTLSEETRQHQ ARAQYQDKLARQRYEDQLKQQQLLN EENLRKQEESVQKQEAMRRATVERE MELRHKNEMLRVEAEARARAKAERE NADITREQIRLKAAEHRQTVLESIR TAGTLFGEGFRAFVTDWDKVTATVA GLTLLAVGVYSAKNATLVAGRFIEA RLGKPSLVRETSRITVLEALRHPIQ VSRRLLSRPQDALEGVVLSPSLEAR VRDIAIATRNTKKNRSLYRNILMYG PPGTGKTLFAKKLALHSGMDYAIMT GGDVAPMGREGVTAMHKLFDWANTS RRGLLLFVDEADAFLRKRATEKISE DLRATLNAFLYRTGQHSNKFMLVLA SNQPEQFDWAINDRINEMVHFDLPG QEERERLVRMYFDKYVLKPATEGKQ RLKLAQFDYGRKCSEVARLTEGMSG REIAQLAVSWQATAYASEDGVLTEA MMDTRVQDAVQQHQQKMCWLKAEGP GRGDEPSPS
Applications : Enzyme-linked Immunoabsorbent Assay; Western Blot (Recombinant protein); Antibody Production; Protein Array
Notes : Best use within three months from the date of receipt of this protein.
Storage : Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing.
Storage Buffer : 50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.
Gene Name : ATAD3A ATPase family, AAA domain containing 3A [ Homo sapiens ]
Official Symbol : ATAD3A
Synonyms : ATAD3A; ATPase family, AAA domain containing 3A; ATPase family AAA domain-containing protein 3A; FLJ10709; FLJ35514;
Gene ID : 55210
mRNA Refseq : NM_001170535
Protein Refseq : NP_001164006
MIM : 612316
UniProt ID : Q9NVI7

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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