Recombinant Human ATAD3B protein, GST-tagged

• Cat.No.: ATAD3B-931H
• Product Overview: Human ATAD3B full-length ORF ( AAH02542.1, 1 a.a. - 648 a.a.) recombinant protein with GST-tag at N-terminal.

Specification

• Description: The protein encoded by this gene is localized to the mitochondrial inner membrane, where it can bind to a highly-related protein, ATAD3A. ATAD3A appears to interact with matrix nucleoid complexes, and the encoded protein negatively regulates that interaction. This gene is expressed almost exclusively in pluripotent embryonic stem cells and some cancer cells. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Nov 2015]
• Source: Wheat Germ
• Species: Human
• Tag: GST
• Molecular Mass: 99 kDa
• AA Sequence: MSWLFGVNKGPKGEGAGPPPPLPPA QPGAEGGGDRGLGDRPAPKDKWSNF DPTGLERAAKAARELEHSRYAKEAL NLAQMQEQTLQLEQQSKLKEYEAAV EQLKSEQIRAQAEERRKTLSEETRQ HQARAQYQDKLARQRYEDQLKQQRL LNEENLRKQEESVQKQEAMRRATVE REMELRHKNEMLRVETEARARAKAE RENADIIREQIRLKASEHRQTVLES IRTAGTLFGEGFRAFVTDRDKVTAT VAGLTLLAVGVYSAKNATAVTGRFI EARLGKPSLVRETSRITVLEALRHP IQVSRRLLSRPQDVLEGVVLSPSLE ARVRDIAIATRNTKKNRGLYRHILL YGPPGTGKTLFAKKLALHSGMDYAI MTGGDVAPMGREGVTAMHKLFDWAN TSRRGLLLFMDEADAFLRKRATEEI SKDLRATLNAFLYHMGQHSNKFMLV LASNLPEQFDCAINSRIDVMVHFDL PQQEERERLVRLHFDNCVLKPATEG KRRLKLAQFDYGRKCSEVARLTEGM SGREIAQLAVSWQATAYASKDGVLT EAMMDACVQDAVQQYRQKMRWLKAE GPGRGVEHPLSGVQGETLTSWSLAT DPSYPCLAGPCTFRICSWMGTGLCP GPLSPRMSCGGGRPFCPPGHPLL
• Applications: Enzyme-linked Immunoabsorbent Assay; Western Blot (Recombinant protein); Antibody Production; Protein Array
• Notes: Best use within three months from the date of receipt of this protein.
• Storage: Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing.
• Storage Buffer: 50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.

Gene Information

• Gene Name: ATAD3B ATPase family, AAA domain containing 3B [ Homo sapiens ]
• Official Symbol: ATAD3B
• Synonyms: ATAD3B; ATPase family, AAA domain containing 3B; ATPase family AAA domain-containing protein 3B; KIAA1273; TOB3; AAA-ATPase TOB3; AAA-TOB3
• Gene ID: 83858
• mRNA Refseq: NM_031921
• Protein Refseq: NP_114127
• MIM: 612317
• UniProt ID: Q5T9A4