Recombinant Human ATF7 Protein, Myc/DDK-tagged, C13 and N15-labeled

• Cat.No.: ATF7-1022H
• Product Overview: ATF7 MS Standard C13 and N15-labeled recombinant protein (NP_001123531) with a C-terminal MYC/DDK tag, was expressed in HEK293 cells.

Specification

• Description: Isoform 5 acts as a negative regulator, inhibiting both ATF2 and ATF7 transcriptional activities. It may exert these effects by sequestrating in the cytoplasm the Thr-53 phosphorylating kinase, preventing activation.
• Source: HEK293
• Species: Human
• Tag: Myc/DDK
• Molecular Mass: 52.8 kDa
• AA Sequence: MGDDRPFVCNAPGCGQRFTNEDHLA VHKHKHEMTLKFGPARTDSVIIADQ TPTPTRFLKNCEEVGLFNELASSFE HEFKKAADEDEKKARSRTVAKKLVA AAGPLDMSLPSTPDIKIKEEEPVEV DSSPPDSPASSPCSPPLKEKEVTPK PVLISTPTPTIVRPGSLPLHLGYDP LHPTLPSPTSVITQAPPSNRQMGSP TGSLPLVMHLANGQTMPVLPGPPVQ MPSVISLARPVSMVPNIPGIPGPPV NSSGSISPSGHPIPSEAKMRLKATL THQVSSINGGCGMVVGTASTMVTAR PEQSQILIQHPDAPSPAQPQVSPAQ PTPSTGGRRRRTVDEDPDERRQRFL ERNRAAASRCRQKRKLWVSSLEKKA EELTSQNIQLSNEVTLLRNEVAQLK QLLLAHKDCPVTALQKKTQGYLESP KESSEPTGSPAPVIQHSSATAPSNG LSVRSAAEAVATSVLTQMASQRTEL SMPIQSHVIMTPQSQSAGRTRTRPL EQKLISEEDLAANDILDYKDDDDKV
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Stability: Stable for 3 months from receipt of products under proper storage and handling conditions.
• Storage: Store at -80 centigrade. Avoid repeated freeze-thaw cycles.
• Concentration: 50 μg/mL as determined by BCA
• Storage Buffer: 100 mM glycine, 25 mM Tris-HCl, pH 7.3.

Gene Information

• Gene Name: ATF7 activating transcription factor 7 [ Homo sapiens (human) ]
• Official Symbol: ATF7
• Synonyms: ATF7; activating transcription factor 7; cyclic AMP-dependent transcription factor ATF-7; ATFA; transcription factor ATF-A; MGC57182
• Gene ID: 11016
• mRNA Refseq: NM_001130059
• Protein Refseq: NP_001123531
• MIM: 606371
• UniProt ID: P17544