Recombinant Human ATIC Protein, Myc/DDK-tagged, C13 and N15-labeled
Cat.No. : | ATIC-4383H |
Product Overview : | ATIC MS Standard C13 and N15-labeled recombinant protein (NP_004035) with a C-terminal MYC/DDK tag, was expressed in HEK293 cells. |
- Specification
- Gene Information
- Related Products
Description : | This gene encodes a bifunctional protein that catalyzes the last two steps of the de novo purine biosynthetic pathway. The N-terminal domain has phosphoribosylaminoimidazolecarboxamide formyltransferase activity, and the C-terminal domain has IMP cyclohydrolase activity. A mutation in this gene results in AICA-ribosiduria. |
Source : | HEK293 |
Species : | Human |
Tag : | Myc/DDK |
Molecular Mass : | 64.6 kDa |
AA Sequence : | MAPGQLALFSVSDKTGLVEFARNLT ALGLNLVASGGTAKALRDAGLAVRD VSELTGFPEMLGGRVKTLHPAVHAG ILARNIPEDNADMARLDFNLIRVVA CNLYPFVKTVASPGVTVEEAVEQID IGGVTLLRAAAKNHARVTVVCEPED YVVVSTEMQSSESKDTSLETRRQLA LKAFTHTAQYDEAISDYFRKQYSKG VSQMPLRYGMNPHQTPAQLYTLQPK LPITVLNGAPGFINLCDALNAWQLV KELKEALGIPAAASFKHVSPAGAAV GIPLSEDEAKVCMVYDLYKTLTPIS AAYARARGADRMSSFGDFVALSDVC DVPTAKIISREVSDGIIAPGYEEEA LTILSKKKNGNYCVLQMDQSYKPDE NEVRTLFGLHLSQKRNNGVVDKSLF SNVVTKNKDLPESALRDLIVATIAV KYTQSNSVCYAKNGQVIGIGAGQQS RIHCTRLAGDKANYWWLRHHPQVLS MKFKTGVKRAEISNAIDQYVTGTIG EDEDLIKWKALFEEVPELLTEAEKK EWVEKLTEVSISSDAFFPFRDNVDR AKRSGVAYIAAPSGSAADKVVIEAC DELGIILAHTNLRLFHHTRTRPLEQ KLISEEDLAANDILDYKDDDDKV |
Purity : | > 80% as determined by SDS-PAGE and Coomassie blue staining |
Stability : | Stable for 3 months from receipt of products under proper storage and handling conditions. |
Storage : | Store at -80 centigrade. Avoid repeated freeze-thaw cycles. |
Concentration : | 50 μg/mL as determined by BCA |
Storage Buffer : | 100 mM glycine, 25 mM Tris-HCl, pH 7.3. |
Gene Name : | ATIC 5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase/IMP cyclohydrolase [ Homo sapiens (human) ] |
Official Symbol : | ATIC |
Synonyms : | ATIC; 5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase/IMP cyclohydrolase; bifunctional purine biosynthesis protein PURH; AICARFT; IMPCHASE; phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase; PURH; AICARFT/IMPCHASE; AICAR formyltransferase/IMP cyclohydrolase bifunctional enzyme; 5-aminoimidazole-4-carboxamide-1-beta-D-ribonucleotide transformylase/inosinicase; AICAR; FLJ93545; |
Gene ID : | 471 |
mRNA Refseq : | NM_004044 |
Protein Refseq : | NP_004035 |
MIM : | 601731 |
UniProt ID : | P31939 |
Products Types
◆ Recombinant Protein | ||
Atic-365M | Recombinant Mouse Atic Protein, MYC/DDK-tagged | +Inquiry |
ATIC-831M | Recombinant Mouse ATIC Protein, His (Fc)-Avi-tagged | +Inquiry |
ATIC-503R | Recombinant Rat ATIC Protein, His (Fc)-Avi-tagged | +Inquiry |
ATIC-398H | Recombinant Human ATIC Protein, His (Fc)-Avi-tagged | +Inquiry |
ATIC-6733C | Recombinant Chicken ATIC | +Inquiry |
◆ Lysates | ||
ATIC-8618HCL | Recombinant Human ATIC 293 Cell Lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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