Recombinant Human ATL1 Protein, Myc/DDK-tagged, C13 and N15-labeled

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Recombinant Human ATL1 Protein, Myc/DDK-tagged, C13 and N15-labeled

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Cat.No. : ATL1-1062H
Product Overview : ATL1 MS Standard C13 and N15-labeled recombinant protein (NP_056999) with a C-terminal MYC/DDK tag, was expressed in HEK293 cells.
Description : The protein encoded by this gene is a GTPase and a Golgi body transmembrane protein. The encoded protein can form a homotetramer and has been shown to interact with spastin and with mitogen-activated protein kinase kinase kinase kinase 4. This protein may be involved in axonal maintenance as evidenced by the fact that defects in this gene are a cause of spastic paraplegia type 3. Three transcript variants encoding two different isoforms have been found for this gene.
Source : HEK293
Species : Human
Tag : Myc/DDK
Molecular Mass : 63.4 kDa
AA Sequence : MAKNRRDRNS WGGFSEKTYE WSSEEEEPVK KAGPVQVLIV KDEHSFELDE TALNRILLSE AVRDKEVVAV SVAGAFRKGK SFLMDFMLRY MYNQESVDWV GDYNEPLTGF SWRGGSERET TGIQIWSEIF LINKPDGKKV AVLLMDTQGT FDSQSTLRDS ATVFALSTMI SSIQVYNLSQ NVQEDDLQHL QLCTEYGRLA MEETFLKPFQ SLIFLVRDWS FPYEFSYGAD GGAKFLEKRL KVSGNQHEEL QNVRKHIHSC FTNISCFLLP HPGLKVATNP NFDGKLKEID DEFIKNLKIL IPWLLSPESL DIKEINGNKI TCRGLVEYFK AYIKIYQGEE LPHPKSMLQA TAEANNLAAV ATAKDTYNKK MEEICGGDKP FLAPNDLQTK HLQLKEESVK LFRGVKKMGG EEFSRRYLQQ LESEIDELYI QYIKHNDSKN IFHAARTPAT LFVVIFITYV IAGVTGFIGL DIIASLCNMI MGLTLITLCT WAYIRYSGEY RELGAVIDQV AAALWDQGST NEALYKLYSA AATHRHLYHQ AFPTPKSEST EQSEKKKMTR TRPLEQKLIS EEDLAANDIL DYKDDDDKV
Purity : > 80% as determined by SDS-PAGE and Coomassie blue staining
Stability : Stable for 3 months from receipt of products under proper storage and handling conditions.
Storage : Store at -80 centigrade. Avoid repeated freeze-thaw cycles.
Concentration : 50 μg/mL as determined by BCA
Storage Buffer : 100 mM glycine, 25 mM Tris-HCl, pH 7.3.
SDS-PAGE :

Gene Name : ATL1 atlastin GTPase 1 [ Homo sapiens (human) ]
Official Symbol : ATL1
Synonyms : ATL1; atlastin GTPase 1; spastic paraplegia 3A (autosomal dominant), SPG3, SPG3A; atlastin-1; AD FSP; atlastin; FSP1; GBP-3; hGBP3; GTP-binding protein 3; guanylate-binding protein 3; spastic paraplegia 3 protein A; brain-specific GTP-binding protein; guanine nucleotide-binding protein 3; GBP3; SPG3; HSN1D; SPG3A; AD-FSP; atlastin1;
Gene ID : 51062
mRNA Refseq : NM_015915
Protein Refseq : NP_056999
MIM : 606439
UniProt ID : Q8WXF7

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