Recombinant Human ATP1A3 protein, GST-tagged

• Cat.No.: ATP1A3-963H
• Product Overview: Human ATP1A3 full-length ORF ( NP_689509.1, 1 a.a. - 1013 a.a.) recombinant protein with GST-tag at N-terminal.

Specification

• Description: The protein encoded by this gene belongs to the family of P-type cation transport ATPases, and to the subfamily of Na+/K+ -ATPases. Na+/K+ -ATPase is an integral membrane protein responsible for establishing and maintaining the electrochemical gradients of Na and K ions across the plasma membrane. These gradients are essential for osmoregulation, for sodium-coupled transport of a variety of organic and inorganic molecules, and for electrical excitability of nerve and muscle. This enzyme is composed of two subunits, a large catalytic subunit (alpha) and a smaller glycoprotein subunit (beta). The catalytic subunit of Na+/K+ -ATPase is encoded by multiple genes. This gene encodes an alpha 3 subunit. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jan 2012]
• Source: Wheat Germ
• Species: Human
• Tag: GST
• Molecular Mass: 138.1 kDa
• AA Sequence: MGDKKDDKDSPKKNKGKERRDLDDL KKEVAMTEHKMSVEEVCRKYNTDCV QGLTHSKAQEILARDGPNALTPPPT TPEWVKFCRQLFGGFSILLWIGAIL CFLAYGIQAGTEDDPSGDNLYLGIV LAAVVIITGCFSYYQEAKSSKIMES FKNMVPQQALVIREGEKMQVNAEEV VVGDLVEIKGGDRVPADLRIISAHG CKVDNSSLTGESEPQTRSPDCTHDN PLETRNITFFSTNCVEGTARGVVVA TGDRTVMGRIATLASGLEVGKTPIA IEIEHFIQLITGVAVFLGVSFFILS LILGYTWLEAVIFLIGIIVANVPEG LLATVTVCLTLTAKRMARKNCLVKN LEAVETLGSTSTICSDKTGTLTQNR MTVAHMWFDNQIHEADTTEDQSGTS FDKSSHTWVALSHIAGLCNRAVFKG GQDNIPVLKRDVAGDASESALLKCI ELSSGSVKLMRERNKKVAEIPFNST NKYQLSIHETEDPNDNRYLLVMKGA PERILDRCSTILLQGKEQPLDEEMK EAFQNAYLELGGLGERVLGFCHYYL PEEQFPKGFAFDCDDVNFTTDNLCF VGLMSMIDPPRAAVPDAVGKCRSAG IKVIMVTGDHPITAKAIAKGVGIIS EGNETVEDIAARLNIPVSQVNPRDA KACVIHGTDLKDFTSEQIDEILQNH TEIVFARTSPQQKLIIVEGCQRQGA IVAVTGDGVNDSPALKKADIGVAMG IAGSDVSKQAADMILLDDNFASIVT GVEEGRLIFDNLKKSIAYTLTSNIP EITPFLLFIMANIPLPLGTITILCI DLGTDMVPAISLAYEAAESDIMKRQ PRNPRTDKLVNERLISMAYGQIGMI QALGGFFSYFVILAENGFLPGNLVG IRLNWDDRTVNDLEDSYGQQWTYEQ RKVVEFTCHTAFFVSIVVVQWADLI ICKTRRNSVFQQGMKNKILIFGLFE ETALAAFLSYCPGMDVALRMYPLKP SWWFCAFPYSFLIFVYDEIRKLILR RNPGGWVEKETYY
• Applications: Enzyme-linked Immunoabsorbent Assay; Western Blot (Recombinant protein); Antibody Production; Protein Array
• Notes: Best use within three months from the date of receipt of this protein.
• Storage: Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing.
• Storage Buffer: 50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.

Gene Information

• Gene Name: ATP1A3 ATPase, Na+/K+ transporting, alpha 3 polypeptide [ Homo sapiens ]
• Official Symbol: ATP1A3
• Synonyms: ATP1A3; ATPase, Na+/K+ transporting, alpha 3 polypeptide; dystonia 12 , DYT12; sodium/potassium-transporting ATPase subunit alpha-3; Na+/K+ ATPase 3; sodium pump subunit alpha-3; Na(+)/K(+) ATPase alpha-3 subunit; Na(+)/K(+) ATPase alpha(III) subunit; sodium-potassium-ATPase, alpha 3 polypeptide; sodium/potassium-transporting ATPase alpha-3 chain; RDP; DYT12; MGC13276
• Gene ID: 478
• mRNA Refseq: NM_001256213
• Protein Refseq: NP_001243142
• MIM: 182350
• UniProt ID: P13637