| Description : |
This gene encodes one of the SERCA Ca(2+)-ATPases, which are intracellular pumps located in the sarcoplasmic or endoplasmic reticula of muscle cells. This enzyme catalyzes the hydrolysis of ATP coupled with the translocation of calcium from the cytosol to the sarcoplasmic reticulum lumen, and is involved in calcium sequestration associated with muscular excitation and contraction. Alternative splicing results in multiple transcript variants encoding different isoforms. |
| Source : |
HEK293 |
| Species : |
Human |
| Tag : |
Myc/DDK |
| Molecular Mass : |
114.8 kDa |
| AA Sequence : |
MEAAHLLPAADVLRHFSVTAEGGLS PAQVTGARERYGPNELPSEEGKSLW ELVLEQFEDLLVRILLLAALVSFVL AWFEEGEETTTAFVEPLVIMLILVA NAIVGVWQERNAESAIEALKEYEPE MGKVIRSDRKGVQRIRARDIVPGDI VEVAVGDKVPADLRLIEIKSTTLRV DQSILTGESVSVTKHTEAIPDPRAV NQDKKNMLFSGTNITSGKAVGVAVA TGLHTELGKIRSQMAAVEPERTPLQ RKLDEFGRQLSHAISVICVAVWVIN IGHFADPAHGGSWLRGAVYYFKIAV ALAVAAIPEGLPAVITTCLALGTRR MARKNAIVRSLPSVETLGCTSVICS DKTGTLTTNQMSVCRMFVVAEADAG SCLLHEFTISGTTYTPEGEVRQGDQ PVRCGQFDGLVELATICALCNDSAL DYNEAKGVYEKVGEATETALTCLVE KMNVFDTDLQALSRVERAGACNTVI KQLMRKEFTLEFSRDRKSMSVYCTP TRPHPTGQGSKMFVKGAPESVIERC SSVRVGSRTAPLTPTSREQILAKIR DWGSGSDTLRCLALATRDAPPRKED MELDDCSKFVQYETDLTFVGCVGML DPPRPEVAACITRCYQAGIRVVMIT GDNKGTAVAICRRLGIFGDTEDVAG KAYTGREFDDLSPEQQRQACRTARC FARVEPAHKSRIVENLQSFNEITAM TGDGVNDAPALKKAEIGIAMGSGTA VAKSAAEMVLSDDNFASIVAAVEEG RAIYSNMKQFIRYLISSNVGEVVCI FLTAILGLPEALIPVQLLWVNLVTD GLPATALGFNPPDLDIMEKLPRSPR EALISGWLFFRYLAIGVYVGLATVA AATWWFVYDAEGPHINFYQLRNFLK CSEDNPLFAGIDCEVFESRFPTTMA LSVLVTIEMCNALNSVSENQSLLRM PPWMNPWLLVAVAMSMALHFLILLV PPLPLIFQVTPLSGRQWVVVLQISL PVILLDEALKYLSRNHMHACLYPGL LRTVSQAWSRQPLTTSWTPDHTGLA SLGQGHSIVSLSELLREGGSREEMS QKTRTRPLEQKLISEEDLAANDILD YKDDDDKV |
| Purity : |
> 80% as determined by SDS-PAGE and Coomassie blue staining |
| Stability : |
Stable for 3 months from receipt of products under proper storage and handling conditions. |
| Storage : |
Store at -80 centigrade. Avoid repeated freeze-thaw cycles. |
| Concentration : |
50 μg/mL as determined by BCA |
| Storage Buffer : |
100 mM glycine, 25 mM Tris-HCl, pH 7.3. |
