Recombinant Human ATP6AP1 protein, GST-tagged

• Cat.No.: ATP6AP1-992H
• Product Overview: Human ATP6AP1 full-length ORF ( NP_001174.2, 1 a.a. - 470 a.a.) recombinant protein with GST-tag at N-terminal.

Specification

• Description: This gene encodes a component of a multisubunit enzyme that mediates acidification of eukaryotic intracellular organelles. Vacuolar ATPase (V-ATPase) is comprised of a cytosolic V1 (site of the ATP catalytic site) and a transmembrane V0 domain. V-ATPase dependent organelle acidification is necessary for such intracellular processes as protein sorting, zymogen activation, and receptor-mediated endocytosis. The encoded protein of this gene may assist in the V-ATPase-mediated acidification of neuroendocrine secretory granules. This protein may also play a role in early development. [provided by RefSeq, Aug 2013]
• Source: Wheat Germ
• Species: Human
• Tag: GST
• Molecular Mass: 78.4 kDa
• AA Sequence: MMAAMATARVRMGPRCAQALWRMPW LPVFLSLAAAAAAAAAEQQVPLVLW SSDRDLWAPAADTHEGHITSDLQLS TYLDPALELGPRNVLLFLQDKLSIE DFTAYGGVFGNKQDSAFSNLENALD LAPSSLVLPAVDWYAVSTLTTYLQE KLGASPLHVDLATLRELKLNASLPA LLLIRLPYTASSGLMAPREVLTGND EVIGQVLSTLKSEDVPYTAALTAVR PSRVARDVAVVAGGLGRQLLQKQPV SPVIHPPVSYNDTAPRILFWAQNFS VAYKDQWEDLTPLTFGVQELNLTGS FWNDSFARLSLTYERLFGTTVTFKF ILANRLYPVSARHWFTMERLEVHSN GSVAYFNASQVTGPSIYSFHCEYVS SLSKKGSLLVARTQPSPWQMMLQDF QIQAFNVMGEQFSYASDCASFFSPG IWMGLLTSLFMLFIFTYGLHMILSL KTMDRFDDHKGPTISLTQIV
• Applications: Enzyme-linked Immunoabsorbent Assay; Western Blot (Recombinant protein); Antibody Production; Protein Array
• Notes: Best use within three months from the date of receipt of this protein.
• Storage: Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing.
• Storage Buffer: 50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.

Gene Information

• Gene Name: ATP6AP1 ATPase, H+ transporting, lysosomal accessory protein 1 [ Homo sapiens ]
• Official Symbol: ATP6AP1
• Synonyms: ATP6AP1; ATPase, H+ transporting, lysosomal accessory protein 1; ATP6IP1, ATP6S1, ATPase, H+ transporting, lysosomal (vacuolar proton pump), subunit 1; V-type proton ATPase subunit S1; 16A; Ac45; CF2; ORF; VATPS1; XAP 3; XAP3; protein XAP-3; H-ATPase subunit; V-ATPase subunit S1; V-ATPase Ac45 subunit; V-ATPase S1 accessory protein; vacuolar proton pump subunit S1; ATPase, H+ transporting, lysosomal interacting protein 1; ATPase, H+ transporting, lysosomal (vacuolar proton pump), subunit 1; XAP-3; ATP6S1; ATP6IP1; MGC129781
• Gene ID: 537
• mRNA Refseq: NM_001183
• Protein Refseq: NP_001174
• MIM: 300197
• UniProt ID: Q15904