Recombinant Human AXL Receptor Tyrosine Kinase, His-tagged, Active

Cat.No. : AXL-249H
Product Overview : Recombinant human AXL (473-end) was expressed by baculovirus inSf9 insect cellsusing an N-terminal His tag. MW = 55 kDa.
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Cat. No. : AXL-249H
Description : AXL is a member of the receptor tyrosine kinase family which has oncogenic potential and is implicated in human myeloid leukemia. AXL is a member of a complex signaling network that is involved in the control of cell proliferation and differentiation. Overexpression of AXL cDNA in NIH 3T3 cells induces neoplastic transformation of these cells with the concomitant appearance of a 140kDa AXL tyrosine-phosphorylated protein. Expression of AXL cDNA in the baculovirus system results in the expression of the appropriate recombinant protein that is recognized by antiphosphotyrosine antibodies, confirming that the AXL protein is tyrosine phosphorylated.
Source : Sf9 insect cells using baculovirus.
Sequence : 473-end.
Applications : Kinase Assay, Western Blot.
Storage And Stability : Store product at –70°C. For optimal storage, aliquot target into smaller quantities after centrifugation and store at recommended temperature. For most favorable performance, avoid repeated handling and multiple freeze/thaw cycles.
Protein length : 473-end
Gene Name : AXL AXL receptor tyrosine kinase [ Homo sapiens ]
Synonyms : AXL receptor tyrosine kinase; UFO; JTK11; AXL; oncogene AXL; AXL transforming sequence/gene; EC 2.7.10.1; AXL oncogene
Gene ID : 558
mRNA Refseq : NM_001699
Protein Refseq : NP_001690
MIM : 109135
UniProt ID : P30530
Chromosome Location : 19q13.1
Function : transmembrane receptor protein tyrosine kinase activity; ATP binding; nucleotide binding; protein binding; receptor activity; transferase activity

Not For Human Consumption!

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