Recombinant Human B-Cell CLL/Lymphoma 2, His-tagged
Cat.No. : | BCL2-5296H |
Product Overview : | Recombinanthuman BCL2 with His Tag was expressed in E. coli. |
- Specification
- Gene Information
- Related Products
Cat. No. : | BCL2-5296H |
Description : | Recombinanthuman BCL2 with His Tag, excluding the BH4 domain, which corresponds to aminoacids 10-30. This is a single, non-glycosylated polypeptide chain containing197 amino acid residues consisting of amino acids 1-9 and 31-218. |
Source : | E. coli |
Species : | Human |
Form : | Lyophilized from asterile filtered solution containing 10 mM Tris-HCl, pH 8.0 + 1 mM EDTA + 250mM NaCl. |
Purity : | > 95% asdetermined by RP-HPLC and SDS-PAGE analyses. |
Storage : | Store lyophilizedprotein at -20°C to -80°C. Reconstituted protein is stable for 1 week at2-4°C. For long term storage, aliquot and store at -20°C to -80°C with acarrier protein (0.1% HSA or BSA) as a stabilizer. Please note that theaddition of any carrier protein into this product may produce unwantedendotoxin. This depends upon the particular application employed. Avoidrepeated freeze-thaw cycles. |
OfficialSymbol : | BCL2 |
Gene Name : | BCL2 B-cell CLL/lymphoma 2 [ Homosapiens ] |
Synonyms : | BCL2; B-cellCLL/lymphoma 2; Bcl-2; PPP1R50; apoptosisregulator Bcl-2; protein phosphatase 1, regulatory subunit 50 |
Gene ID : | 596 |
mRNA Refseq : | NM_000633 |
Protein Refseq : | NP_000624 |
MIM : | 151430 |
UniProt ID : | P10415 |
Chromosome Location : | 18q21.33; 18q21.3 |
Pathway : | ATF-2 transcriptionfactor network; Activation of BAD and translocation to mitochondria;Activation of BH3-only proteins; Amyotrophic lateral sclerosis (ALS);Apoptosis; B Cell Receptor Signaling Pathway; BH3-only proteins associatewith and inactivate anti-apoptotic BCL-2 members; Caspase cascade inapoptosis; Cholinergic synapse; Colorectal cancer; RXR and RARheterodimerization with other nuclear receptor; Small cell lung cancer; TheNLRP1 inflammasome; Toxoplasmosis; Tuberculosis |
Function : | BH3 domain binding;channel activity; identical protein binding; protease binding; protein binding;protein heterodimerization activity; protein homodimerization activity;protein phosphatase 2A binding; sequence-specific DNA binding; transcriptionfactor binding; ubiquitin protein ligase binding |
Products Types
◆ Recombinant Protein | ||
BCL2-2469H | Recombinant Human BCL2 Protein, MYC/DDK-tagged | +Inquiry |
BCL2-438H | Recombinant Human BCL2 Protein, His (Fc)-Avi-tagged | +Inquiry |
BCL2-22H | Recombinant Human BCL2 Protein | +Inquiry |
Bcl2-304R | Recombinant Rat Bcl2 Protein, His-tagged | +Inquiry |
BCL2-2627H | Recombinant Human BCL2 protein(31-100 aa), N-SUMO & C-His-tagged | +Inquiry |
◆ Assay kits | ||
Kit-1686 | BCL-2 TR-FRET Assay Kit | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
Inquiry
0
Inquiry Basket