Recombinant Human B2M & HLA-A protein(NY-ESO-1)(SLLMWITQC), His-tagged
Cat.No. : | B2M & HLA-A-892H |
Product Overview : | Recombinant Human HLA-A*0201 NY-ESO-1 complex Protein is produced by our Mammalian expression system and the target gene encoding (SLLMWITQC)&Ile21-Met119&Gly25-Ile308 (Ala269Val) is expressed with a 10His tag at the C-terminus. |
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Description : | NY-ESO-1 is a well-known cancer-testis antigen (CTAs) with re-expression in numerous cancer types. Its ability to elicit spontaneous humoral and cellular immune responses, together with its restricted expression pattern, have rendered it a good candidate target for cancer immunotherapy. Optimally assembled peptide-HLA-B2M trimer translocates to the surface of antigen-presenting cells, where it interacts with TCR and CD8 coreceptor on the surface of T cells. |
Source : | HEK293 |
Species : | Human |
Tag : | His |
Form : | Lyophilized from a 0.2 μm filtered solution of 20mM PB, 500mM NaCl, pH7.4. |
Molecular Mass : | 55-60kDa, reducing conditions. |
Protein length : | (SLLMWITQC)&Ile21-Met119&Gly25-Ile308 (Ala269Val) |
Endotoxin : | Less than 0.1 ng/µg (1 EU/µg) as determined by LAL test. |
Purity : | Greater than 90% as determined by reducing SDS-PAGE. |
Storage : | Lyophilized protein should be stored at < -20°C, though stable at room temperature for 3 weeks. Reconstituted protein solution can be stored at 4-7°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months. |
Reconstitution : | Always centrifuge tubes before opening. Do not mix by vortex or pipetting. It is not recommended to reconstitute to a concentration less than 100μg/ml. Dissolve the lyophilized protein in distilled water. Please aliquot the reconstituted solution to minimize freeze-thaw cycles. |
Shipping : | The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature listed below. |
Gene Name : | B2M beta-2-microglobulin [ Homo sapiens (human) ] |
Official Symbol : | B2M; HLA-A |
Synonyms : | MHC; MY-ESO-1; HLA-A*0201 NY-ESO-1 complex Protein |
Gene ID : | 567 |
mRNA Refseq : | NM_004048.4 |
Protein Refseq : | NP_004039.1 |
MIM : | 109700 |
UniProt ID : | P61769 |
Products Types
◆ Recombinant Protein | ||
B2M & HLA-A-893H | Recombinant Human B2M & HLA-A protein(GP100)(IMDQVPFSV), His-tagged | +Inquiry |
B2M & HLA-A-895H | Recombinant Human B2M & HLA-A protein(HPV16 E7)(YMLDLQPET), His-tagged | +Inquiry |
B2M & HLA-A-894H | Recombinant Human B2M & HLA-A protein(WT-1)(RMFPNAPYL), His-tagged | +Inquiry |
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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