| Description : |
This gene encodes a member of the peptidase A1 family of aspartic proteases. Alternative splicing results in multiple transcript variants, at least one of which encodes a preproprotein that is proteolytically processed to generate the mature protease. This transmembrane protease catalyzes the first step in the formation of amyloid beta peptide from amyloid precursor protein. Amyloid beta peptides are the main constituent of amyloid beta plaques, which accumulate in the brains of human Alzheimer's disease patients. |
| Source : |
HEK293 |
| Species : |
Human |
| Form : |
Lyophilized |
| Molecular Mass : |
49 kDa |
| Protein Length : |
501 |
| AA Sequence : |
MAQALPWLLLWMGAGVLPAHGTQHG IRLPLRSGLGGAPLGLRLPRETDEE PEEPGRRGSFVEMVDNLRGKSGQGY YVEMTVGSPPQTLNILVDTGSSNFA VGAAPHPFLHRYYQRQLSSTYRDLR KGVYVPYTQGKWEGELGTDLVSIPH GPNVTVRANIAAITESDKFFINGSN WEGILGLAYAEIARPDDSLEPFFDS LVKQTHVPNLFSLQLCGAGFPLNQS EVLASVGGSMIIGGIDHSLYTGSLW YTPIRREWYYEVIIVRVEINGQDLK MDCKEYNYDKSIVDSGTTNLRLPKK VFEAAVKSIKAASSTEKFPDGFWLG EQLVCWQAGTTPWNIFPVISLYLMG EVTNQSFRITILPQQYLRPVEDVAT SQDDCYKFAISQSSTGTVMGAVIME GFYVVFDRARKRIGFAVSACHVHDE FRTAAVEGPFVTLDMEDCGYNIPQT DESTLMTIAYVMAAICALFMLPLCL MVCQWRCLRCLRQQHDDFADDISLL K |
| Purity : |
> 98% |
| Applications : |
WB; ELISA; FACS; FC |
| Stability : |
This bioreagent is stable at 4 centigrade (short-term) and -70 centigrade(long-term). After reconstitution, sample may be stored at 4 centigrade for 2-7 days and below -18 centigrade for future use. |
| Storage : |
At -20 centigrade. |
| Concentration : |
1 mg/mL |
| Storage Buffer : |
PBS (pH 7.4-7.5). Sterile-filtered colorless solution. |
| Reconstitution : |
Reconstitute in sterile distilled H2O to no less than 100 μg/mL; dilute reconstituted stock further in other aqueous solutions if needed. Please review COA for lot-specific instructions. Final measurements should be determined by the end-user for optimal performance. |
