"BACE1" Related Products

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Recombinant Human BACE1 Protein, MYC/DDK-tagged

Cat.No. : BACE1-2200H
Product Overview : Recombinant human BACE1 protein, fused to MYC/DDK-tagged at C-terminus, was expressed in HEK293
Description : This gene encodes a member of the peptidase A1 family of aspartic proteases. Alternative splicing results in multiple transcript variants, at least one of which encodes a preproprotein that is proteolytically processed to generate the mature protease. This transmembrane protease catalyzes the first step in the formation of amyloid beta peptide from amyloid precursor protein. Amyloid beta peptides are the main constituent of amyloid beta plaques, which accumulate in the brains of human Alzheimer's disease patients. [provided by RefSeq, Nov 2015].
Source : HEK293
Species : Human
Tag : MYC/DDK
Form : 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.
Molecular Mass : 51 kDa
Purity : > 80% as determined by SDS-PAGE and Coomassie blue staining
Concentration : >50 ug/mL as determined by microplate BCA method
Gene Name : BACE1 beta-site APP-cleaving enzyme 1 [ Homo sapiens ]
Official Symbol : BACE1
Synonyms : ASP2; BACE; HSPC104
Gene ID : 23621
mRNA Refseq : NM_001207048
Protein Refseq : NP_001193977
MIM : 604252
UniProt ID : P56817

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