Recombinant Human BACE2 protein, MYC/DDK-tagged

• Cat.No.: BACE2-579H
• Product Overview: Recombinant Human BACE2, transcript variant a, fused with MYC/DDK tag at C-terminal was expressed in HEK293.

Specification

• Species: Human
• Source: HEK293
• Tag: DDK&Myc
• Form: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.
• Molecular Mass: 49.8 kDa
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Notes: Recombinant protein was captured through anti-DDK affinity column followed by conventional chromatography steps.
• Concentration: >50 ug/mL as determined by microplate BCA method

Gene Information

• Gene Name: BACE2 beta-site APP-cleaving enzyme 2 [ Homo sapiens ]
• Official Symbol: BACE2
• Synonyms: BACE2; beta-site APP-cleaving enzyme 2; AEPLC; beta-secretase 2; ALP56; CEAP1; DRAP; asp 1; memapsin-1; theta-secretase; beta secretase 2; aspartyl protease 1; 56 kDa aspartic-like protease; aspartic-like protease 56 kDa; down region aspartic protease; beta-site APP cleaving enzyme 2; Down syndrome region aspartic protease; transmembrane aspartic proteinase Asp1; membrane-associated aspartic protease 1; beta-site amyloid precursor protein cleaving enzyme 2; beta-site amyloid beta A4 precursor protein-cleaving enzyme 2; ASP1; BAE2; ASP21; CDA13
• Gene ID: 25825
• mRNA Refseq: NM_012105
• Protein Refseq: NP_036237
• MIM: 605668
• UniProt ID: Q9Y5Z0
• Chromosome Location: 21q22.3
• Pathway: Alzheimers disease, organism-specific biosystem; Alzheimers disease, conserved biosystem
• Function: aspartic-type endopeptidase activity; peptidase activity