Recombinant Human Baculoviral IAP Repeat-containing 2

• Cat.No.: BIRC2-2633H
• Product Overview: Recombinant human Baculoviral IAP Repeat-containing 2 (amino acids 1-618) was fused to the peptide sequence MATVIDH10SSNG at the N-terminus and expressed inE. coli. cIAP is a member of the inhibitor of apoptosis family of proteins that inhibits proteolytic activity of mature caspases by interaction of the BIR domain with the active caspase.

Specification

• Species: Human
• Source: E.coli
• Tag: Non
• Description: Baculoviral IAP repeat-containing protein 2 (also known as cIAP1) is a protein that in humans is encoded by the BIRC2 gene. cIAP1 is a member of the Inhibitor of Apoptosis family that inhibit apoptosis by interfering with the activation of caspases.
• Form: Liquid.
• Formulation: Sterile-filtered in 50 mM NaCl, 20 mM HEPES, 1 mM DTT, 20% glycerol, pH 8.0.
• Molar Mass: 72300Da.
• Purity: ≥85% by SDS-PAGE.
• Storage: ≤ -20oC. Ship: Dry Ice Only.

Gene Information

• Gene Name: BIRC2 baculoviral IAP repeat-containing 2 [ Homo sapiens ]
• Synonyms:
  BIRC2; baculoviral IAP repeat-containing 2; IAP homolog B; IAP-2; NFR2-TRAF signalling complex protein; RING finger protein 48; TNFR2-TRAF-signaling complex protein 2; apoptosis inhibitor 1; baculoviral IAP repeat-containing protein 2; inhibitor of apoptosis protein 2; API1; MIHB; HIAP2; RNF48; cIAP1; Hiap-2; c-IAP1
• Gene ID: 329
• mRNA Refseq: NM_001166
• Protein Refseq: NP_001157
• MIM: 601712
• UniProt ID: Q13490
• Chromosome Location: 11q22
• Pathway: Apoptosis; Focal adhesion; NOD-like receptor signaling pathway;Pathways in cancer; Small cell lung cancer; Ubiquitin mediated proteolysis; Apoptosis
• Function: metal ion binding; protein N-terminus binding; protein binding; zinc ion binding